Recombinant Human TNFSF18 protein, His-tagged

• Cat.No.: TNFSF18-36H
• Product Overview: Recombinant Human TNFSF18(aa 50-177) fused with His tag at the N-terminus was expressed in E. coli.

Specification

• Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid, 0.2 um-filtered solution in 55 mM TRIS-Cl, pH 8.2 containing 150 mM NaCl.
• Molecular Mass: 16 kDa(SDS-PAGE)
• Endotoxin: Less than 1.0 EU purified protein(LAL test; Lonza).
• Purity: >90% as determined by SDS-PAGE.
• Stability: Working aliquots are stable for up to 3 months when stored at -20 centigrade.
• Storage: Short Term Storage: 4 centigrade;Longt Term Storage: -20 centigrade.After opening, prepare alipuots and store at -20 centigrade. Avoid freeze/thaw cycles.
• Concentration: 1 mg/ml
• Protein length: 50-177

Gene Information

• Gene Name: TNFSF18 tumor necrosis factor (ligand) superfamily, member 18 [ Homo sapiens ]
• Official Symbol: TNFSF18
• Synonyms: TNFSF18; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand superfamily member 18; AITRL; hGITRL; TL6; AITR ligand; GITR ligand; activation-inducible TNF-related ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; GITRL; MGC138237
• Gene ID: 8995
• mRNA Refseq: NM_005092
• Protein Refseq: NP_005083
• MIM: 603898
• UniProt ID: Q9UNG2
• Chromosome Location: 1q23
• Pathway: Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem
• Function: cytokine activity; receptor binding; tumor necrosis factor receptor binding; tumor necrosis factor receptor superfamily binding