Recombinant Human TNFSF18 protein, His-tagged

• Cat.No.: TNFSF18-507H

Specification

• Product overview: Recombinant Human TNFSF18 (Q9UNG2) aa. (Gln72~Ser199) fused with His tag was produced in HEK293F cells.
• Description: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells.
• Source: HEK293F
• Species: Human
• Tag: His
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 16.1kDa; Accurate Molecular Mass: 15&18kDa as determined by SDS-PAGE reducing conditions.
• Protein length: Gln72~Ser199
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: > 97%
• Characteristic: Isoelectric point is 6.1.
• Applications: SDS-PAGE; WB; ELISA; IP; CoIP; EMSA; Reporter Assays; Purification; Amine Reactive Labeling
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Concentration: 200ug/mL
• Storage buffer: 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in 20mM Tris, 150mM NaCl (pH8.0) to a concentration of 0.1-1.0 mg/mL. Do not vortex

Gene Information

• Gene Name: TNFSF18 TNF superfamily member 18 [ Homo sapiens (human) ]
• Official Symbol: TNFSF18
• Synonyms: TNFSF18; TNF superfamily member 18; TL6; AITRL; GITRL; TNLG2A; hGITRL; tumor necrosis factor ligand superfamily member 18; AITR ligand; activation-inducible TNF-related ligand; GITR ligand; glucocorticoid-induced TNF-related ligand; glucocorticoid-induced TNFR-related protein ligand; tumor necrosis factor (ligand) superfamily, member 18; tumor necrosis factor ligand 2A; tumor necrosis factor superfamily member 18
• Gene ID: 8995
• mRNA Refseq: NM_005092.3
• Protein Refseq: NP_005083.2
• UniProt ID: Q9UNG2