Recombinant Human TNFSF9 Protein, His-tagged
Cat.No. : | TNFSF9-2019H |
Product Overview : | Recombinant Human 4-1BB Ligand/TNFSF9 Protein is produced by E. coli expression system. The target protein is expressed with sequence (Arg71-Glu254) of human 4-1BB Ligand/TNFSF9 (Accession #NP_003802.1) fused with a 6×His tag at the C-terminus. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This transmembrane cytokine is a bidirectional signal transducer that acts as a ligand for TNFRSF9/4-1BB, which is a costimulatory receptor molecule in T lymphocytes. This cytokine and its receptor are involved in the antigen presentation process and in the generation of cytotoxic T cells. The receptor TNFRSF9/4-1BB is absent from resting T lymphocytes but rapidly expressed upon antigenic stimulation. The ligand encoded by this gene, TNFSF9/4-1BBL, has been shown to reactivate anergic T lymphocytes in addition to promoting T lymphocyte proliferation. This cytokine has also been shown to be required for the optimal CD8 responses in CD8 T cells. This cytokine is expressed in carcinoma cell lines, and is thought to be involved in T cell-tumor cell interaction. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4, 5 % trehalose, 5 % mannitol. |
Protein length : | Arg71-Glu254 |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 90% as determined by SDS-PAGE |
Stability : | Samples are stable for up to twelve months from date of receipt at -70ºC. |
Storage : | Store it under sterile conditions at -20ºC~-70ºC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Gene Name : | TNFSF9 tumor necrosis factor (ligand) superfamily, member 9 [ Homo sapiens ] |
Official Symbol : | TNFSF9 |
Synonyms : | TNFSF9; tumor necrosis factor (ligand) superfamily, member 9; tumor necrosis factor ligand superfamily member 9; 4 1BB L; homolog of mouse 4 1BB L; receptor 4 1BB ligand; 4-1BBL; 4-1BB ligand; receptor 4-1BB ligand; homolog of mouse 4-1BB-L; CD137L; 4-1BB-L; |
Gene ID : | 8744 |
mRNA Refseq : | NM_003811 |
Protein Refseq : | NP_003802 |
MIM : | 606182 |
UniProt ID : | P41273 |
Products Types
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TNFSF9-322H | Recombinant Active Human TNFSF9 Protein, His-tagged(C-ter) | +Inquiry |
TNFSF9-231H | Active Recombinant Human TNFSF9 Protein (Leu 24 - Gln 186), His-tagged | +Inquiry |
TNFSF9-157H | Recombinant Human TNFSF9 Protein, FLAG-tagged | +Inquiry |
◆ Lysates | ||
TNFSF9-1445RCL | Recombinant Rat TNFSF9 cell lysate | +Inquiry |
TNFSF9-1444RCL | Recombinant Rat TNFSF9 cell lysate | +Inquiry |
TNFSF9-2810MCL | Recombinant Mouse TNFSF9 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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