Recombinant Human TOLLIP Protein, His-tagged

• Cat.No.: TOLLIP-511H
• Product Overview: Recombinant Human TOLLIP fused with His tag at C-terminal was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: This gene encodes a ubiquitin-binding protein that interacts with several Toll-like receptor (TLR) signaling cascade components. The encoded protein regulates inflammatory signaling and is involved in interleukin-1 receptor trafficking and in the turnover of IL1R-associated kinase. Several transcript variants encoding different isoforms have been found for this gene.
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM Phosphate buffer, 150mM NaCl, 5mM EDTA, pH 7.2. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
• Molecular Mass: 31.3 kDa
• Endotoxin: < 0.1 EU per µg protein as determined by LAL test
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Resuspend the protein to the desired concentration in proper buffer.

Gene Information

• Gene Name: TOLLIP toll interacting protein [ Homo sapiens ]
• Official Symbol: TOLLIP
• Synonyms: TOLLIP; toll interacting protein; toll-interacting protein; IL 1RAcPIP; adapter protein; IL-1RAcPIP; FLJ33531
• Gene ID: 54472
• mRNA Refseq: NM_019009
• Protein Refseq: NP_061882
• MIM: 606277
• UniProt ID: Q9H0E2