Recombinant Human TOP2A
Cat.No. : | TOP2A-115H |
Product Overview : | Recombinant enzyme overexpressed in a proprietary eukaryotic cell line. |
- Specification
- Gene Information
- Related Products
Description : | Topoisomerase II α (TopoIIα) is a gene product with conserved catalytic activities and it promotes the progression of DNA damage. The α isoform is present in proliferating cells. |
Species : | Human |
Form : | Solution in 10 mM Tris-HCl, pH 7.1, 0.25 M NaCl, 1 mM EDTA, 0.5 mM PMSF, 1 mM 2-mercaptoethanol, 10% glycerol. |
Molecular Mass : | mol wt 170 kDa |
Unit Definition : | One unit will decatenate 0.2 μg of kinetoplast DNA in 30 minutes at 37°C. |
Storage : | Store at −70°C |
Gene Name : | TOP2A topoisomerase (DNA) II alpha 170kDa [ Homo sapiens ] |
Official Symbol : | TOP2A |
Synonyms : | TOP2A; topoisomerase (DNA) II alpha 170kDa; TOP2, topoisomerase (DNA) II alpha (170kD); DNA topoisomerase 2-alpha; DNA gyrase; DNA topoisomerase II, 170 kD; DNA topoisomerase (ATP-hydrolyzing); DNA topoisomerase II, alpha isozyme; TOP2; TP2A; |
Gene ID : | 7153 |
mRNA Refseq : | NM_001067 |
Protein Refseq : | NP_001058 |
MIM : | 126430 |
UniProt ID : | P11388 |
Chromosome Location : | 17q21-q22 |
Pathway : | Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; G0 and Early G1, organism-specific biosystem; Mitotic G1-G1/S phases, organism-specific biosystem; |
Function : | ATP binding; DNA binding; DNA topoisomerase (ATP-hydrolyzing) activity; DNA-dependent ATPase activity; chromatin binding; drug binding; enzyme binding; histone deacetylase binding; nucleotide binding; protein C-terminus binding; protein binding; protein heterodimerization activity; protein homodimerization activity; protein kinase C binding; sequence-specific DNA binding; structure-specific DNA binding; ubiquitin binding; |
Products Types
◆ Recombinant Protein | ||
TOP2A-2638H | Recombinant Human TOP2A protein(1051-1240 aa), C-His-tagged | +Inquiry |
TOP2A-5882R | Recombinant Rat TOP2A Protein, His (Fc)-Avi-tagged | +Inquiry |
TOP2A-9519M | Recombinant Mouse TOP2A Protein, His (Fc)-Avi-tagged | +Inquiry |
TOP2A-4231H | Recombinant Human TOP2A Protein, His (Fc)-Avi-tagged | +Inquiry |
TOP2A-6489H | Recombinant Human TOP2A Protein (Ile923-Arg1148), N-His tagged | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
0
Inquiry Basket