Recombinant Human TOR1AIP2 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TOR1AIP2-683H
• Product Overview: TOR1AIP2 MS Standard C13 and N15-labeled recombinant protein (NP_659471) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: One of the two protein isoforms encoded by this gene is a type II integral membrane protein found in the endoplasmic reticulum (ER). The encoded protein is a cofactor for the ATPase TorsinA, regulating the amount of TorsinA present in the ER compared to that found in the nuclear envelope. Defects in this protein are a cause of early onset primary dystonia, a neuromuscular disease. The other isoform encoded by this gene is an interferon alpha responsive protein whose cellular role has yet to be determined.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.3 kDa
• AA Sequence: MADSGLREPQEDSQKDLENDPSVNS QAQETTIIASNAEEAEILHSACGLS KDHQEVETEGPESADTGDKSESPDE ANVGKHPKDKTEDENKQSFLDGGKG HHLPSENLGKEPLDPDPSHSPSDKV GRADAHLGSSSVALPKEASDGTGAS QEPPTTDSQEAQSPGHSSAGQEGED TLRRRLLAPEAGSHPQQTQKLEEIK ENAQDTMRQINKKGFWSYGPVILVV LVVAVVASSVNSYYSSPAQQVPKNP ALEAFLAQFSQLEDKFPGQSSFLWQ RGRKFLQKHLNASNPTEPATIIFTA AREGRETLKCLSHHVADAYTSSQKV SPIQIDGAGRTWQDSDTVKLLVDLE LSYGFENGQKAAVVHHFESFPAGST LIFYKYCDHENAAFKDVALVLTVLL EEETLEASVGPRETEEKVRDLLWAK FTNSDTPTSFNHMDSDKLSGLWSRI SHLVLPVQPVSSIEEQGCLFTRTRP LEQKLISEEDLAANDILDYKDDDDK V
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TOR1AIP2 torsin 1A interacting protein 2 [ Homo sapiens (human) ]
• Official Symbol: TOR1AIP2
• Synonyms: TOR1AIP2; torsin 1A interacting protein 2; NET9; LULL1; IFRG15; torsin-1A-interacting protein 2; interferon alpha responsive protein; 15 kDa interferon-responsive protein; interferon responsive gene 15; lumenal domain like LAP1; torsin A interacting protein 2
• Gene ID: 163590
• mRNA Refseq: NM_145034
• Protein Refseq: NP_659471
• MIM: 614513
• UniProt ID: Q8NFQ8