Recombinant Human TREM1 protein(Met1-Arg200), His&hFc-tagged
Cat.No. : | TREM1-886H |
Product Overview : | Recombinant Human TREM1 (NP_061113.1)(Met 1-Arg 200) was expressed in HEK293, fused with the C-terminal polyhistidine-tagged Fc region of Human IgG1 at the C-terminus. |
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Source : | HEK293 |
Species : | Human |
Tag : | C-His&hFc |
Protein length : | Met1-Arg200 |
Form : | Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. |
Molecular Mass : | The recombinant human TREM1/Fc is a disulfide-linked homodimer after removal of the signal peptide. The reduced monomer consists of 428 amino acids and has a predicted molecular mass of 48.3 kDa. In SDS-PAGE under reducing conditions, the apparent molecular mass of rhTREM1/Fc monomer is approximately 60-65 kDa due to glycosylation. |
Endotoxin : | < 1.0 EU per μg of the protein as determined by the LAL method. |
Purity : | > 95 % as determined by SDS-PAGE |
Storage : | Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents. |
Gene Name : | TREM1 triggering receptor expressed on myeloid cells 1 [ Homo sapiens ] |
Official Symbol : | TREM1 |
Synonyms : | TREM1; triggering receptor expressed on myeloid cells 1; CD354; TREM 1; triggering-receptor TREM1; triggering receptor expressed on monocytes 1; TREM-1; |
Gene ID : | 54210 |
mRNA Refseq : | NM_001242589 |
Protein Refseq : | NP_001229518 |
MIM : | 605085 |
UniProt ID : | Q9NP99 |
Products Types
◆ Recombinant Protein | ||
TREM1-3842H | Recombinant Human TREM1 protein(Met1-Arg200), His-tagged | +Inquiry |
TREM1-116H | Recombinant Human TREM1 Protein, C-His-tagged | +Inquiry |
TREM1-485H | Recombinant Human TREM1 Protein, His-tagged | +Inquiry |
TREM1-30119TH | Recombinant Human TREM1, His-tagged | +Inquiry |
TREM1-125R | Recombinant Rhesus Monkey TREM1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
TREM1-2140HCL | Recombinant Human TREM1 cell lysate | +Inquiry |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Q&As (6)
Ask a questionTREM1 protein can enhance inflammatory response during infection, but its specific relationship with antibacterial effect still needs further study.
High expression of the TREM1 protein in lung disease can trigger an excessive inflammatory response, and controlling its activity may help reduce the symptoms and inflammatory damage of lung disease.
When bacterial infection occurs, the expression of the TREM1 protein increases, which enhances the inflammatory response, which helps clear the infection and regulate the inflammatory process.
TREM1 protein is involved in immune response processes such as macrophage activation, release of inflammatory mediators, and recruitment and regulation of immune cells.
The study of TREM1 protein helps to understand the regulatory mechanism of inflammatory response and provide new targets and strategies for the treatment of inflammatory diseases.
High expression of the TREM1 protein is associated with the development and prognosis of certain diseases and can therefore serve as a biomarker for predicting and monitoring disease progression.
Customer Reviews (3)
Write a reviewThe exceptional stability of TREM1 makes it an invaluable tool for a wide range of applications.
Manufacturer's commitment to environmental sustainability is evident in its production processes, using green and renewable resources.
TREM1 has a short half-life, making it more effective and less likely to cause side effects compared to other similar proteins.
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