Recombinant Human TRMT6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: TRMT6-6368H
• Product Overview: TRMT6 MS Standard C13 and N15-labeled recombinant protein (NP_057023) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the tRNA methyltransferase 6 protein family. A similar protein in yeast is part of a two component methyltransferase, which is involved in the posttranslational modification that produces the modified nucleoside 1-methyladenosine in tRNAs. Modified 1-methyladenosine influences initiator methionine stability and may be involved in the replication of human immunodeficiency virus type 1. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 55.8 kDa
• AA Sequence: MEGSGEQPGPQPQHPGDHRIRDGDF VVLKREDVFKAVQVQRRKKVTFEKQ WFYLDNVIGHSYGTAFEVTSGGSLQ PKKKREEPTAETKEAGTDNRNIVDD GKSQKLTQDDIKALKDKGIKGEEIV QQLIENSTTFRDKTEFAQDKYIKKK KKKYEAIITVVKPSTRILSIMYYAR EPGKINHMRYDTLAQMLTLGNIRAG NKMIVMETCAGLVLGAMMERMGGFG SIIQLYPGGGPVRAATACFGFPKSF LSGLYEFPLNKVDSLLHGTFSAKML SSEPKDSALVEESNGTLEEKQASEQ ENEDSMAEAPESNHPEDQETMETIS QDPEHKGPKERGSKKDYIQEKQRRQ EEQRKRHLEAAALLSERNADGLIVA SRFHPTPLLLSLLDFVAPSRPFVVY CQYKEPLLECYTKLRERGGVINLRL SETWLRNYQVLPDRSHPKLLMSGGG GYLLSGFTVAMDNLKADTSLKSNAS TLESHETEEPAAKKRKCPESDSTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: TRMT6 tRNA methyltransferase 6 [ Homo sapiens (human) ]
• Official Symbol: TRMT6
• Synonyms: TRMT6; tRNA methyltransferase 6 homolog (S. cerevisiae); tRNA (adenine(58)-N(1))-methyltransferase non-catalytic subunit TRM6; CGI 09; GCD10; Gcd10p; MGC5029; tRNA(m1A58)MTase subunit TRM6; tRNA(m1A58)-methyltransferase subunit TRM6; tRNA (adenine-N(1)-)-methyltransferase non-catalytic subunit TRM6; CGI-09
• Gene ID: 51605
• mRNA Refseq: NM_015939
• Protein Refseq: NP_057023
• UniProt ID: Q9UJA5