Recombinant Human TSEN34 Protein, His-tagged

• Cat.No.: TSEN34-2800H
• Product Overview: Recombinant Human TSEN34 protein, fused to His-tagged at N-terminus, was expressed in E. coli.

Specification

• Description: This gene encodes a catalytic subunit of the tRNA splicing endonuclease, which catalyzes the removal of introns from precursor tRNAs. The endonuclease complex is also associated with a pre-mRNA 3-prime end processing factor. A mutation in this gene results in the neurological disorder pontocerebellar hypoplasia type 2. Multiple alternatively spliced variants, encoding the same protein, have been identified.
• Source: E. coli
• Species: Human
• Tag: His
• Form: 25 mM Tris, pH 8.0, 150 mM NaCl, 10% glycerol, 1% Sarkosyl.
• Molecular Mass: 33.5 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 ug/mL as determined by microplate BCA method

Gene Information

• Gene Name: TSEN34 tRNA splicing endonuclease 34 homolog (S. cerevisiae) [ Homo sapiens ]
• Official Symbol: TSEN34
• Synonyms: LENG5; PCH2C; SEN34; SEN34L
• Gene ID: 79042
• mRNA Refseq: NM_001077446
• Protein Refseq: NP_001070914
• MIM: 608754
• UniProt ID: Q9BSV6