Description : |
This gene encodes a protein with a tetratricopeptide repeat (TPR) domain containing several TPRs of about 34 aa each. These repeats are found in a variety of organisms including bacteria, fungi and plants, and are involved in a variety of functions including protein-protein interactions. This protein is embedded in the inner mitochondrial membrane and is involved in the formation of the mitochondrial respiratory chain III. It has also been suggested that this protein plays a role in cytokinesis. Mutations in this gene cause mitochondrial complex III deficiency. Alternatively spliced transcript variants have been found for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
55.6 kDa |
AA Sequence : |
MAQPHTTSVPYFARSPAPPPPSRSG APPQPPATLRPSRRRTRPPRPADRR DAPADCAYLWRILTPRRGRARRSDV GARHRACGRRDVLLSRQGPANPEGA RRVVGGQERVWPAVRRGRGGSMFRL LSWSLGRGFLRAAGRRCRGCSARLL PGLAGGPGPEVQVPPSRVAPHGRGP GLLPLLAALAWFSRPAAAEEEEQQG ADGAAAEDGADEAEAEIIQLLKRAK LSIMKDEPEEAELILHDALRLAYQT DNKKAITYTYDLMANLAFIRGQLEN AEQLFKATMSYLLGGGMKQEDNAII EISLKLASIYAAQNRQEFAVAGYEF CISTLEEKIEREKELAEDIMSVEEK ANTHLLLGMCLDACARYLLFSKQPS QAQRMYEKALQISEEIQGERHPQTI VLMSDLATTLDAQGRFDEAYIYMQR ASDLARQINHPELHMVLSNLAAVLM HRERYTQAKEIYQEALKQAKLKKDE ISVQHIREELAELSKKSRPLTNSVK LTRTRPLEQKLISEEDLAANDILDY KDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |