Description : |
This gene encodes a member of the Tubby family of bipartite transcription factors. The encoded protein may play a role in obesity and sensorineural degradation. The crystal structure has been determined for a similar protein in mouse, and it functions as a membrane-bound transcription regulator that translocates to the nucleus in response to phosphoinositide hydrolysis. Two transcript variants encoding distinct isoforms have been identified for this gene. |
Source : |
HEK293 |
Species : |
Human |
Tag : |
Myc/DDK |
Molecular Mass : |
55.5 kDa |
AA Sequence : |
MTSKPHSDWIPYSVLDDEGRNLRQQ KLDRQRALLEQKQKKKRQEPLMVQA NADGRPRSRRARQSEEQAPLVESYL SSSGSTSYQVQEADSLASVQLGATR PTAPASAKRTKAAATAGGQGGAARK EKKGKHKGTSGPAALAEDKSEAQGP VQILTVGQSDHAQDAGETAAGGGER PSGQDLRATMQRKGISSSMSFDEDE EDEEENSSSSSQLNSNTRPSSATSR KSVREAASAPSPTAPEQPVDVEVQD LEEFALRPAPQGITIKCRITRDKKG MDRGMYPTYFLHLDREDGKKVFLLA GRKRKKSKTSNYLISVDPTDLSRGG DSYIGKLRSNLMGTKFTVYDNGVNP QKASSSTLESGTLRQELAAVCYETN VLGFKGPRKMSVIVPGMNMVHERVS IRPRNEHETLLARWQNKNTESIIEL QNKTPVWNDDTQSYVLNFHGRVTQA SVKNFQIIHGNDPDYIVMQFGRVAE DVFTMDYNYPLCALQAFAIALSSFD SKLACETRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : |
50 μg/mL as determined by BCA |
Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |