Recombinant Human Tumor-associated Calcium Signal Transducer 2

• Cat.No.: TACSTD2-1694H

Specification

• Cat. No.: TACSTD2-1694H
• Description: Trop-2 is a cell surface glycoprotein that is highly expressed in a wide variety of epithelial cancers. There is little or no expression of Trop-2 in adult somatic tissue. Trop-2 is a novel calcium signal transducer involved in the regulation of cell- cell adhesion. It is an oncogene that has potential as a therapeutic target. It is a possible candidate gene for diagnosis and molecular target therapy of colorectal cancer.
• Molecular Weight: The predicted molecular weight of Recombinant Human TROP-2 is Mr 49.2 kDa. However, the actual molecular weight as observed by migration on SDS Page is Mr 70-80 kDa.
• Source: Mammalian cells
• State Of Matter: Lyophilized.
• Purity: >95% by SDS Page and analyzed by silver stain.
• Endotoxin: <1.0 EU/µg as determined by the LAL method.
• Storage And Stability: This lyophilized protein is stable for six to twelve months when stored desiccated at -20℃ to -70℃. After aseptic reconstitution, this protein may be stored at 2℃ to 8℃ for one month or at -20℃ to -70℃ in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles. See Product Insert for exact lot specific storage instructions.

Gene Information

• Gene Name: TACSTD2 tumor-associated calcium signal transducer 2 [ Homo sapiens ]
• Synonyms: TACSTD2; tumor-associated calcium signal transducer 2; M1S1; EGP-1; GA733; TROP2; GA733-1; epithelial glycoprotein-1; membrane component, chromosome 1, surface marker 1 (40kD glycoprotein, identified by monoclonal antibody GA733); Cell surface glycoprotein Trop-2; Pancreatic carcinoma marker protein GA733-1; OTTHUMP00000011755
• Gene ID: 4070
• mRNA Refseq: NM_002353
• Protein Refseq: NP_002344
• MIM: 137290
• UniProt ID: P09758
• Chromosome Location: 1p32
• Function: receptor activity