Recombinant Human TYR Protein (19-377 aa), His-tagged
Cat.No. : | TYR-1551H |
Product Overview : | Recombinant Human TYR Protein (19-377 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Metabolism. Protein Description: Partial. |
- Specification
- Gene Information
- Related Products
Description : | This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone. |
Source : | Yeast |
Species : | Human |
Tag : | His |
Form : | Tris-based buffer,50% glycerol |
Molecular Mass : | 42.7 kDa |
Protein length : | 19-377 aa |
AA Sequence : | HFPRACVSSKNLMEKECCPPWSGDR SPCGQLSGRGSCQNILLSNAPLGPQ FPFTGVDDRESWPSVFYNRTCQCSG NFMGFNCGNCKFGFWGPNCTERRLL VRRNIFDLSAPEKDKFFAYLTLAKH TISSDYVIPIGTYGQMKNGSTPMFN DINIYDLFVWMHYYVSMDALLGGSE IWRDIDFAHEAPAFLPWHRLFLLRW EQEIQKLTGDENFTIPYWDWRDAEK CDICTDEYMGGQHPTNPNLLSPASF FSSWQIVCSRLEEYNSHQSLCNGTP EGPLRRNPGNHDKSRTPRLPSSADV EFCLSLTQYESGSMDKAANFSFRNT LEGFASPLTGIADASQSSMHNALHI YMNGTMSQV |
Purity : | > 90% as determined by SDS-PAGE. |
Notes : | Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week. |
Storage : | The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade. |
Concentration : | A hardcopy of COA with reconstitution instruction is sent along with the products. |
Gene Name : | TYR tyrosinase (oculocutaneous albinism IA) [ Homo sapiens ] |
Official Symbol : | TYR |
Synonyms : | TYR; tyrosinase; OCAIA; LB24-AB; SK29-AB; CMM8; OCA1A; SHEP3; |
Gene ID : | 7299 |
mRNA Refseq : | NM_000372 |
Protein Refseq : | NP_000363 |
MIM : | 606933 |
UniProt ID : | P14679 |
Products Types
◆ Recombinant Protein | ||
Tyr-6757M | Recombinant Mouse Tyr Protein, Myc/DDK-tagged | +Inquiry |
TYR-2965H | Recombinant Human TYR Protein, MYC/DDK-tagged | +Inquiry |
Tyr-518R | Recombinant Rat Tyr Protein, His-tagged | +Inquiry |
TYR-9798M | Recombinant Mouse TYR Protein, His (Fc)-Avi-tagged | +Inquiry |
TYR-238H | Recombinant Human TYR Protein, MYC/DDK-tagged, C13 and N15-labeled | +Inquiry |
◆ Lysates | ||
TYR-1869HCL | Recombinant Human TYR cell lysate | +Inquiry |
◆ Assay kits | ||
Kit-0836 | Tyrosine Colorimetric Assay Kit | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
Inquiry
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Q&As (6)
Ask a questionThere are no drugs that directly increase TYR protein levels, but there are drugs that can treat diseases that cause low TYR protein levels.
This protein may play a role in skin aging because it is involved in the production and metabolism of melanin. However, skin aging is also related to other factors, such as genetics, environment, etc.
Some whitening products claim to inhibit the TYR protein, thereby reducing the production of melanin. However, the efficacy and safety of these products have yet to be proven.
It is difficult to directly increase the level of TYR protein through diet because TYR protein is mainly genetically determined. However, the presence of copper in the diet can promote the function of the TYR protein.
TYR is not directly related to tanning. Tanning is a process by which skin cells produce melanin due to ultraviolet rays.
TYR protein may be involved in the occurrence and progression of skin cancer because it is involved in the production and metabolism of melanin.
Customer Reviews (3)
Write a reviewRepeatability is good, the results of multiple experiments are highly consistent, and the repeatability is particularly good.
High solubility, can be dissolved in various types of reagents, easy to operate.
Not easy to inactivate, tried a variety of experimental conditions, still active.
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