Recombinant Human TYR Protein (19-377 aa), His-tagged

• Cat.No.: TYR-1551H
• Product Overview: Recombinant Human TYR Protein (19-377 aa) is produced by Yeast expression system. This protein is fused with a 6xHis tag at the N-terminal. Research Area: Metabolism. Protein Description: Partial.

Specification

• Description: This is a copper-containing oxidase that functions in the formation of pigments such as melanins and other polyphenolic compounds. Catalyzes the rate-limiting conversions of tyrosine to DOPA, DOPA to DOPA-quinone and possibly 5,6-dihydroxyindole to indole-5,6 quinone.
• Source: Yeast
• Species: Human
• Tag: His
• Form: Tris-based buffer,50% glycerol
• Molecular Mass: 42.7 kDa
• Protein length: 19-377 aa
• AA Sequence: HFPRACVSSKNLMEKECCPPWSGDR SPCGQLSGRGSCQNILLSNAPLGPQ FPFTGVDDRESWPSVFYNRTCQCSG NFMGFNCGNCKFGFWGPNCTERRLL VRRNIFDLSAPEKDKFFAYLTLAKH TISSDYVIPIGTYGQMKNGSTPMFN DINIYDLFVWMHYYVSMDALLGGSE IWRDIDFAHEAPAFLPWHRLFLLRW EQEIQKLTGDENFTIPYWDWRDAEK CDICTDEYMGGQHPTNPNLLSPASF FSSWQIVCSRLEEYNSHQSLCNGTP EGPLRRNPGNHDKSRTPRLPSSADV EFCLSLTQYESGSMDKAANFSFRNT LEGFASPLTGIADASQSSMHNALHI YMNGTMSQV
• Purity: > 90% as determined by SDS-PAGE.
• Notes: Repeated freezing and thawing is not recommended. Store working aliquots at 4 centigrade for up to one week.
• Storage: The shelf life is related to many factors, storage state, buffer ingredients, storage temperature and the stability of the protein itself. Generally, the shelf life of liquid form is 6 months at -20 centigrade/-80 centigrade. The shelf life of lyophilized form is 12 months at -20 centigrade/-80 centigrade.
• Concentration: A hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: TYR tyrosinase (oculocutaneous albinism IA) [ Homo sapiens ]
• Official Symbol: TYR
• Synonyms: TYR; tyrosinase; OCAIA; LB24-AB; SK29-AB; CMM8; OCA1A; SHEP3
• Gene ID: 7299
• mRNA Refseq: NM_000372
• Protein Refseq: NP_000363
• MIM: 606933
• UniProt ID: P14679