Recombinant Human UBAC1 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: UBAC1-3561H
• Product Overview: UBAC1 MS Standard C13 and N15-labeled recombinant protein (NP_057256) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Non-catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 45.3 kDa
• AA Sequence: MFVQEEKIFAGKVLRLHICASDGAE WLEEATEDTSVEKLKERCLKHCAHG SLEDPKSITHHKLIHAASERVLSDA RTILEENIQDQDVLLLIKKRAPSPL PKMADVSAEEKKKQDQKAPDKEAIL RATANLPSYNMDRAAVQTNMRDFQT ELRKILVSLIEVAQKLLALNPDAVE LFKKANAMLDEDEDERVDEAALRQL TEMGFPENRATKALQLNHMSVPQAM EWLIEHAEDPTIDTPLPGQAPPEAE GATAAASEAAAGASATDEEARDELT EIFKKIRRKREFRADARAVISLMEM GFDEKEVIDALRVNNNQQNAACEWL LGDRKPSPEELDKGIDPDSPLFQAI LDNPVVQLGLTNPKTLLAFEDMLEN PLNSTQWMNDPETGPVMLQISRIFQ TLNRTTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: UBAC1 UBA domain containing 1 [ Homo sapiens (human) ]
• Official Symbol: UBAC1
• Synonyms: UBAC1; UBA domain containing 1; UBADC1, ubiquitin associated domain containing 1; ubiquitin-associated domain-containing protein 1; GBDR1; UBA domain-containing protein 1; E3 ubiquitin-protein ligase subunit KPC2; ubiquitin associated domain containing 1; kip1 ubiquitination-promoting complex protein 2; glialblastoma cell differentiation-related protein 1; putative glialblastoma cell differentiation-related protein; UBADC1; RP11-432J22.3
• Gene ID: 10422
• mRNA Refseq: NM_016172
• Protein Refseq: NP_057256
• MIM: 608129
• UniProt ID: Q9BSL1