Recombinant Human UBE2A Protein, His-tagged, Active

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Recombinant Human UBE2A Protein, His-tagged, Active

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Cat.No. : UBE2A-642H
Product Overview : Recombinant Human UBE2A fused with His tag at N-terminal was expressed in E. coli.
Description : UBE2A or ubiquitin-conjugating enzyme E2A is a member of the E2 ubiquitin-conjugating enzyme family which is required for post-replicative DNA damage repair and plays an important role in various cellular processes. RAD18 and RAD5 play a central role in mediating physical contacts between the members of the RAD6 pathway. UBE2A is specifically important during chronic low dose ultraviolet exposure to prevent counterproductive DNA checkpoint activation and allow cells to proliferate normally. Loss of the RAD6 error-free PRR pathway results in DNA damage checkpoint-induced G2 arrest in CLUV-exposed cells.
Source : E. coli
Species : Human
Tag : His
Form : 50mM sodium phosphate, pH 7.0, 300mM NaCl, 150mM imidazole, 0.1mM PMSF, 0.25mM DTT, 25% glycerol
Bio-activity : 30 nmol/min/mg
Molecular Mass : 17 kDa
Purity : >95%
Applications : Ubiquitin Enzyme Assay, Western Blot
Stability : 1 year at - 70 centigrade from the date of shipment.
Storage : Store product at –70 centigrade. For optimal storage, aliquot target into smaller quantities after centrifugation and store at recommended temperature. For most favorable performance, avoid repeated handling and multiple freeze/thaw cycles.
Concentration : 0.1 ug/ml
Figure :

Gene Name : UBE2A ubiquitin-conjugating enzyme E2A [ Homo sapiens ]
Official Symbol : UBE2A
Synonyms : UBE2A; ubiquitin-conjugating enzyme E2A; ubiquitin conjugating enzyme E2A (RAD6 homolog); ubiquitin-conjugating enzyme E2 A; HHR6A; RAD6A; UBC2; HR6A; RAD6 homolog A; ubiquitin-protein ligase A; ubiquitin carrier protein A; ubiquitin-conjugating enzyme E2A (RAD6 homolog); MRXSN; MRXS30;
Gene ID : 7319
mRNA Refseq : NM_003336
Protein Refseq : NP_003327
MIM : 312180
UniProt ID : P49459
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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