Recombinant Human UBE2E2 Protein, His-tagged

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Recombinant Human UBE2E2 Protein, His-tagged

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Cat.No. : UBE2E2-311H
Product Overview : Recombinant Human UBE2E2 Protein is produced by Bacteria expression system. This protein is fused with a His tag.
Description : Ube2E2 is an E2 enzyme, which is part of the E1, E2, and E3 cascade responsible for ubiquitination of protein substrates. It shares 96% identical amino acid sequence with Ube2E1 and Ube2E3 with the exception of the N-terminal extension that has little in common with the other two E2s. Ube2E2 interacts with ARA54 and RNF8. The RNF8/ Ube2E2 interaction is found to catalyze K48-linked poly-ubiquitination. Ube2E2 may play a role in ubiquitination and subsequent proteasomal degradation of the E3 Ub ligase Parkin.
Source : Bacteria
Species : Human
Tag : His
Form : 20 mM Tris, 150 mM NaCl, 2 mM βME, 10% Glycerol
Molecular Mass : 22.3 kDa
Purity : > 90 % by SDS-PAGE
Storage : Store at -80 centigrade; avoid multiple freeze-thaw cycles.
UBE2E2-311H, 1 :

Coomassie-stained SDS-PAGE<br />Lane 1: Molecular weight markers<br />Lane 2: 5 µg purified6xHis-Ube2E2 (UbcH8)

Gene Name : UBE2E2 ubiquitin-conjugating enzyme E2E 2 ( Homo sapiens )
Official Symbol : UBE2E2
Synonyms : UBCH8
Gene ID : 7325
mRNA Refseq : NM_152653
Protein Refseq : NP_689866
MIM : 602163
UniProt ID : Q96LR5

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