Recombinant Human UBQLN2 protein, His-tagged

• Cat.No.: UBQLN2-46H
• Product Overview: Recombinant human UBQLN2, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-624 aa
• Description: UBQLN2 also known as ubiquilin-2. Ubiquilins contain an N-terminal ubiquitin-like domain and a C-terminal ubiquitin-associated domain. They physically associate with both proteasomes and ubiquitin ligases, and are thus thought to functionally link the ubiquitination machinery to the proteasome to effect in vivo protein degradation.
• Form: Liquid. In Phosphate Buffered Saline (pH7.4) containing 20% glycerol, 1mM DTT
• Molecular Mass: 68.1kDa (647aa)
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMAENGES SGPPRPSRGP AAAQGSAAAP AEPKIIKVTV KTPKEKEEFA VPENSSVQQF KEAISKRFKSQTDQLVLIFA GKILKDQDTL IQHGIHDGLT VHLVIKSQNR PQGQSTQPSN AAGTNTTSAS TPRSNSTPIS TNSNPFGLGS LGGLAGLSSLGLSSTNFSEL QSQMQQQLMA SPEMMIQIME NPFVQSMLSN PDLMRQLIMA NPQMQQLIQR NPEISHLLNN PDIMRQTLEI ARNPAMMQEMMRNQDLALSN LESIPGGYNA LRRMYTDIQE PMLNAAQEQF GGNPFASVGS SSSSGEGTQP SRTENRDPLP NPWAPPPATQ SSATTSTTTSTGSGSGNSSS NATGNTVAAA NYVASIFSTP GMQSLLQQIT ENPQLIQNML SAPYMRSMMQ SLSQNPDLAA QMMLNSPLFT ANPQLQEQMRPQLPAFLQQM QNPDTLSAMS NPRAMQALMQ IQQGLQTLAT EAPGLIPSFT PGVGVGVLGT AIGPVGPVTP IGPIGPIVPF TPIGPIGPIG PTGPAAPPGS TGSGGPTGPT VSSAAPSETT SPTSESGPNQ QFIQQMVQAL AGANAPQLPN PEVRFQQQLE QLNAMGFLNR EANLQALIATGGDINAAIER LLGSQPS
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.25 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: UBQLN2 ubiquilin 2 [ Homo sapiens ]
• Official Symbol: UBQLN2
• Synonyms: UBQLN2; ubiquilin 2; ubiquilin-2; Chap1; CHAP1/DSK2; Dsk2; LIC 2; N4BP4; NEDD4 binding protein 4; PLIC 2; PLIC2; RIHFB2157; Nedd4 binding protein 4; ubiquitin-like product Chap1/Dsk2; protein linking IAP with cytoskeleton 2; DSK2; ALS15; CHAP1; HRIHFB2157; FLJ10167; FLJ56541
• Gene ID: 29978
• mRNA Refseq: NM_013444
• Protein Refseq: NP_038472
• MIM: 300264
• UniProt ID: Q9UHD9
• Chromosome Location: Xp11.21
• Pathway: Protein processing in endoplasmic reticulum, organism-specific biosystem; Protein processing in endoplasmic reticulum, conserved biosystem
• Function: protein binding