Recombinant Human UBR5 Protein, GST-tagged

• Cat.No.: UBR5-4053H
• Product Overview: Human EDD1 partial ORF ( NP_056986, 2677 a.a. - 2774 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: This gene encodes a progestin-induced protein, which belongs to the HECT (homology to E6-AP carboxyl terminus) family. The HECT family proteins function as E3 ubiquitin-protein ligases, targeting specific proteins for ubiquitin-mediated proteolysis. This gene is localized to chromosome 8q22 which is disrupted in a variety of cancers. This gene potentially has a role in regulation of cell proliferation or differentiation. [provided by RefSeq, Jul 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 36.52 kDa
• AA Sequence: LLVNGCGEVNVQMLISFTSFNDESG ENAEKLLQFKRWFWSIVEKMSMTER QDLVYFWTSSPSLPASEEGFQPMPS ITIRPPDDQHLPTANTCISRLYV
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: UBR5 ubiquitin protein ligase E3 component n-recognin 5 [ Homo sapiens ]
• Official Symbol: UBR5
• Synonyms: UBR5; ubiquitin protein ligase E3 component n-recognin 5; E3 ubiquitin protein ligase, HECT domain containing, 1 , EDD1; E3 ubiquitin-protein ligase UBR5; DD5; EDD; HYD; KIAA0896; hHYD; ubiquitin-protein ligase; progestin induced protein; progestin-induced protein; hyperplastic discs protein homolog; E3 identified by differential display; E3 ubiquitin-protein ligase, HECT domain-containing 1; E3 ubiquitin protein ligase, HECT domain containing, 1; EDD1; FLJ11310; MGC57263
• Gene ID: 51366
• mRNA Refseq: NM_015902
• Protein Refseq: NP_056986
• MIM: 608413
• UniProt ID: O95071