Recombinant Human UBTD2 protein, His-tagged

• Cat.No.: UBTD2-110H
• Product Overview: Recombinant Human UBTD2, fused with N-terminal His tag, was expressed in E.coli.

Specification

• Description: Interferes with CBL-mediated down-regulation and degradation of receptor-type tyrosine kinases. Promotes accumulation of activated target receptors, such as T-cell receptors and EGFR, on the cell surface. Exhibits tyrosine phosphatase activity toward several substrates including EGFR, FAK, SYK, and ZAP70. Down-regulates proteins that are dually modified by both protein tyrosine phosphorylation and ubiquitination.
• Source: E.coli
• Species: Human
• Tag: His
• Form: 20mM Tris.Cl, 50mM NaCl, 50% Glycerol, pH8.0.
• Molecular Mass: 23.5kDa(including fusion tag)
• Protein length: 205aa(including fusion tag)
• Applications: WB, ELISA, IP, antibody production, protein array
• Storage: Store at -80centigrade and avoid repeated freeze-thaw cycles.

Gene Information

• Gene Name: UBTD2 ubiquitin domain containing 2 [ Homo sapiens ]
• Official Symbol: UBTD2
• Synonyms: UBTD2; ubiquitin domain containing 2; ubiquitin domain-containing protein 2; DC UbP; dendritic cell derived ubiquitin like protein; MGC30022; ubiquitin-like protein SB72; DCUBP
• Gene ID: 92181
• mRNA Refseq: NM_152277
• Protein Refseq: NP_689490
• MIM: 610174
• UniProt ID: Q8WUN7
• Chromosome Location: 5q35.1