Recombinant Human UPP1, His-tagged

• Cat.No.: UPP1-31675TH
• Product Overview: Recombinant full-length Human Uridine Phosphorylase 1 , with N terminal His tag; 330aa, 36kDa inclusive of tag.

Specification

• Description: The 2 known types of pyrimidine nucleoside phosphorylases, uridine phosphorylase (UP; EC 2.4.2.3) and thymidine phosphorylase (TP; EC 2.4.2.4), in the presence of orthophosphate, catalyze the reversible phosphorolysis of uridine and thymidine or deoxyuridine, respectively, to free bases and ribose-1-phosphate or deoxyribose-1-phosphate.
• Protein length: 310 amino acids
• Conjugation: HIS
• Molecular Weight: 36.000kDa inclusive of tags
• Source: E. coli
• Form: Liquid
• Purity: >90% by SDS-PAGE
• Storage buffer: Preservative: NoneConstituents: 40% Glycerol, 200mM Sodium chloride, 20mM Tris HCl, 1mM DTT, pH 8.0
• Storage: Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSH MAATGANAEK AESHNDCPVR LLNPNIAKMK EDILYHFNLT TSRHNFPALF GDVKFVCVGG SPSRMKAFIRCVGAELGLDC PGRDYPNICA GTDRYAMYKV GPVLSVSHGM GIPSISIMLH ELIKLLYYAR CSNVTIIRIG TSGGIGLEPG TVVITEQAVDTCFKAEFEQI VLGKRVIRKT DLNKKLVQEL LLCSAELSEF TTVVGNTMCT LDFYEGQGRL DGALCSYTEK DKQAYLEAAY AAGVRNIEMESSVFAAMCSA CGLQAAVVCV TLLNRLEGDQ ISSPRNVLSE YQQRPQRLVS YFIKKKLSKA

Gene Information

• Gene Name: UPP1 uridine phosphorylase 1 [ Homo sapiens ]
• Official Symbol: UPP1
• Synonyms: UPP1; uridine phosphorylase 1; UP, uridine phosphorylase; UDRPASE; UPASE; UPP
• Gene ID: 7378
• mRNA Refseq: NM_003364
• Protein Refseq: NP_003355
• MIM: 191730
• Uniprot ID: Q16831
• Chromosome Location: 7p12.3
• Pathway: (deoxy)ribose phosphate degradation, organism-specific biosystem; Drug metabolism - other enzymes, organism-specific biosystem; Drug metabolism - other enzymes, conserved biosystem; Fluoropyrimidine Activity, organism-specific biosystem; Metabolic pathways, organism-specific biosystem
• Function: catalytic activity; uridine phosphorylase activity