Recombinant Human UROD Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: UROD-1672H
• Product Overview: UROD MS Standard C13 and N15-labeled recombinant protein (NP_000365) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes an enzyme in the heme biosynthetic pathway. This enzyme is responsible for catalyzing the conversion of uroporphyrinogen to coproporphyrinogen through the removal of four carboxymethyl side chains. Mutations and deficiency in this enzyme are known to cause familial porphyria cutanea tarda and hepatoerythropoetic porphyria.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 40.8 kDa
• AA Sequence: MEANGLGPQGFPELKNDTFLRAAWG EETDYTPVWCMRQAGRYLPEFRETR AAQDFFSTCRSPEACCELTLQPLRR FPLDAAIIFSDILVVPQALGMEVTM VPGKGPSFPEPLREEQDLERLRDPE VVASELGYVFQAITLTRQRLAGRVP LIGFAGAPWTLMTYMVEGGGSSTMA QAKRWLYQRPQASHQLLRILTDALV PYLVGQVVAGAQALQLFESHAGHLG PQLFNKFALPYIRDVAKQVKARLRE AGLAPVPMIIFAKDGHFALEELAQA GYEVVGLDWTVAPKKARECVGKTVT LQVNLDPCALYASEEEIGQLVKQML DDFGPHRYIANLGHGLYPDMDPEHV GAFVDAVHKHSRLLRQNTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: UROD uroporphyrinogen decarboxylase [ Homo sapiens (human) ]
• Official Symbol: UROD
• Synonyms: UROD; uroporphyrinogen decarboxylase; uroporphyrinogen III decarboxylase; PCT; UPD
• Gene ID: 7389
• mRNA Refseq: NM_000374
• Protein Refseq: NP_000365
• MIM: 613521
• UniProt ID: P06132