Recombinant Human UROS, His-tagged
Cat.No. : | UROS-31079TH |
Product Overview : | Recombinant full length Human UROS with an N terminal His tag; 285 amino acids with a predicted MWt 30.7kDa. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene catalyzes the fourth step of porphyrin biosynthesis in the heme biosynthetic pathway. Defects in this gene cause congenital erythropoietic porphyria (Gunthers disease). |
Protein length : | 265 amino acids |
Conjugation : | HIS |
Molecular Weight : | 30.700kDa inclusive of tags |
Source : | E. coli |
Tissue specificity : | Ubiquitous. |
Form : | Liquid |
Purity : | >95% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 10% Glycerol, 0.1M Sodium chloride, 20mM Tris HCl, pH 8.0 |
Storage : | Store at +4°C short term (1-2 weeks). Aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. |
Sequences of amino acids : | MGSSHHHHHHSSGLVPRGSHMKVLL LKDAKEDDCGQDPYIRELGLYGLEA TLIPVLSFEFLSLPSFSEKLSHPED YGGLIFTSPRAVEAAELCLEQNNKT EVWERSLKEKWNAKSVYVVGNATAS LVSKIGLDTEGETCGNAEKLAEYIC SRESSALPLLFPCGNLKREILPKAL KDKGIAMESITVYQTVAHPGIQGNL NSYYSQQGVPASITFFSPSGLTYSL KHIQELSGDNIDQIKFAAIGPTTAR ALAAQGLPVSCTAESPTPQALATGI RKALQPHGCC |
Sequence Similarities : | Belongs to the uroporphyrinogen-III synthase family. |
Gene Name : | UROS uroporphyrinogen III synthase [ Homo sapiens ] |
Official Symbol : | UROS |
Synonyms : | UROS; uroporphyrinogen III synthase; uroporphyrinogen-III synthase; congenital erythropoietic porphyria; |
Gene ID : | 7390 |
mRNA Refseq : | NM_000375 |
Protein Refseq : | NP_000366 |
MIM : | 606938 |
Uniprot ID : | P10746 |
Chromosome Location : | 10q25.2-q26.3 |
Pathway : | Heme Biosynthesis, organism-specific biosystem; Heme biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism, organism-specific biosystem; Metabolism of porphyrins, organism-specific biosystem; |
Function : | cofactor binding; lyase activity; uroporphyrinogen-III synthase activity; uroporphyrinogen-III synthase activity; |
Products Types
◆ Recombinant Protein | ||
Uros-6858M | Recombinant Mouse Uros Protein, Myc/DDK-tagged | +Inquiry |
UROS-9940M | Recombinant Mouse UROS Protein, His (Fc)-Avi-tagged | +Inquiry |
UROS-4930R | Recombinant Rhesus Macaque UROS Protein, His (Fc)-Avi-tagged | +Inquiry |
UROS-12094Z | Recombinant Zebrafish UROS | +Inquiry |
UROS-17888M | Recombinant Mouse UROS Protein | +Inquiry |
◆ Lysates | ||
UROS-482HCL | Recombinant Human UROS 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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