Recombinant Human USO1, His-tagged
Cat.No. : | USO1-31129TH |
Product Overview : | Recombinant fragment, corresponding to amino acids 746-962 of Human Vesicle docking protein p115 with an N terminal His tag. Predicted mwt: 25 kDa; |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a peripheral membrane protein which recycles between the cytosol and the Golgi apparatus during interphase. It is regulated by phosphorylation: dephosphorylated protein associates with the Golgi membrane and dissociates from the membrane upon phosphorylation. Ras-associated protein 1 recruits this protein to coat protein complex II (COPII) vesicles during budding from the endoplasmic reticulum, where it interacts with a set of COPII vesicle-associated SNAREs to form a cis-SNARE complex that promotes targeting to the Golgi apparatus. Transport from the ER to the cis/medial Golgi compartments requires the action of this gene product, GM130 and giantin in a sequential manner. |
Conjugation : | HIS |
Source : | E. coli |
Form : | Lyophilised:Reconstitute with 130 μl aqua dest. |
Storage buffer : | Preservative: NoneConstituents: 0.5% Trehalose, 6M Urea, 100mM Sodium phosphate, 10mM Sodium chloride, pH 4.5 |
Storage : | Shipped at 4°C. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles. |
Sequences of amino acids : | QELLQSQLTEKDSMIENMKSSQTSGTNEQSSAIVSARDSE QVAELKQELATLKSQLNSQSVEITKLQTEKQELLQKTE AFAKSVEVQGETETIIATKTTDVEGRLSALLQETKELK NEIKALSEERTAIKEQLDSSNSTIAILQTEKDKLELEITD SKKEQDDLLVLLADQDQKILSLKNKLKDLGHPVEEEDE LESGDQEDEDDESEDPGKDLDHI |
Sequence Similarities : | Belongs to the VDP/USO1/EDE1 family.Contains 10 ARM repeats. |
Gene Name : | USO1 USO1 vesicle docking protein homolog (yeast) [ Homo sapiens ] |
Official Symbol : | USO1 |
Synonyms : | USO1; USO1 vesicle docking protein homolog (yeast); USO1 homolog, vesicle docking protein (yeast); general vesicular transport factor p115; p115; TAP; transcytosis associated protein; VDP; vesicle docking protein; |
Gene ID : | 8615 |
mRNA Refseq : | NM_003715 |
Protein Refseq : | NP_003706 |
MIM : | 603344 |
Uniprot ID : | O60763 |
Chromosome Location : | 4q21.1 |
Pathway : | Arf1 pathway, organism-specific biosystem; |
Function : | binding; protein transporter activity; |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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