Recombinant Human USP27X Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: USP27X-5646H
• Product Overview: USP27X MS Standard C13 and N15-labeled recombinant protein (NP_001138545) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the peptidase protein family. The encoded protein functions as a deubiquitinase that is involved in upregulation of the pro-apoptotic Bim protein. This protein may act as a tumor suppressor by increasing levels of Bim to counteract anti-apoptotic signals in cancer cells. Mutations in this gene have been associated with X-linked cognitive disability.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 49.5 kDa
• AA Sequence: MCKDYVYDKDIEQIAKEEQGEALKL QASTSTEVSHQQCSVPGLGEKFPTW ETTKPELELLGHNPRRRRITSSFTI GLRGLINLGNTCFMNCIVQALTHTP ILRDFFLSDRHRCEMPSPELCLVCE MSSLFRELYSGNPSPHVPYKLLHLV WIHARHLAGYRQQDAHEFLIAALDV LHRHCKGDDVGKAANNPNHCNCIID QIFTGGLQSDVTCQACHGVSTTIDP CWDISLDLPGSCTSFWPMSPGRESS VNGESHIPGITTLTDCLRRFTRPEH LGSSAKIKCGSCQSYQESTKQLTMN KLPVVACFHFKRFEHSAKQRRKITT YISFPLELDMTPFMASSKESRMNGQ LQLPTNSGNNENKYSLFAVVNHQGT LESGHYTSFIRHHKDQWFKCDDAVI TKASIKDVLDSEGYLLFYHKQVLEH ESEKVKEMNTQAYTRTRPLEQKLIS EEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: USP27X ubiquitin specific peptidase 27 X-linked [ Homo sapiens (human) ]
• Official Symbol: USP27X
• Synonyms: USP27X; ubiquitin specific peptidase 27 X-linked; USP27; MRX105; USP22L; ubiquitin carboxyl-terminal hydrolase 27; X-linked ubiquitin carboxyl-terminal hydrolase 27; deubiquitinating enzyme 27; ubiquitin specific protease 27, X chromosome; ubiquitin thioesterase 27; ubiquitin-specific-processing protease 27; EC 3.4.19.12
• Gene ID: 389856
• mRNA Refseq: NM_001145073
• Protein Refseq: NP_001138545
• MIM: 300975
• UniProt ID: A6NNY8