Recombinant Human UTP23, Small Subunit (SSU) Processome Component, Homolog (yeast), His-tagged

• Cat.No.: UTP23-7176H
• Product Overview: Recombinant human UTP23 protein, fused to His-tag at N-terminus, was expressed in E. coli and purified by using conventional chromatography techniques. MW: 30.8 kDa.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: 1-249aa
• Description: rRNA-processing protein UTP23 homolog, also known as UTP23, is a small subunit (SSU) processome component. The SSU processome is a complex involved in ribosome biogenesis and is required for pre-18S rRNA maturation. UTP23 is required for the first three cleavage steps in 18S rRNA maturation. In addition, single-point mutations in the conserved putative active site of Utp24 but not Utp23 abrogate its function in ribosome biogenesis.
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.2M NaCl, 20% glycerol,1mM DTT.
• Molecular Mass: 30.8 kDa (272aa) confirmed by MALDI-TOF
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSMKITRQK HAKKHLGFFR NNFGVREPYQ ILLDGTFCQA ALRGRIQLRE QLPRYLMGET QLCTTRCVLK ELETLGKDLY GAKLIAQKCQ VRNCPHFKNA VSGSECLLSM VEEGNPHHYF VATQDQNLSV KVKKKPGVPL MFIIQNTMVL DKPSPKTIAF VKAVESGQLV SVHEKESIKH LKEEQGLVKN TEQSRRKKRK KISGPNPLSC LKKKKKAPDT QSSASEKKRK RKRIRNRSNP KVLSEKQNAE GE
• Purity: >90% by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5 mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: UTP23 UTP23, small subunit (SSU) processome component, homolog (yeast) [ Homo sapiens ]
• Official Symbol: UTP23
• Synonyms: UTP23; UTP23, small subunit (SSU) processome component, homolog (yeast); C8orf53, chromosome 8 open reading frame 53; rRNA-processing protein UTP23 homolog; MGC14595; C8orf53
• Gene ID: 84294
• mRNA Refseq: NM_032334
• Protein Refseq: NP_115710
• UniProt ID: Q9BRU9
• Chromosome Location: 8q24.11