Recombinant Human V-Maf Musculoaponeurotic Fibrosarcoma Oncogene Homolog G (Avian), His-tagged

• Cat.No.: MAFG-4731H
• Product Overview: Recombinant human MAFG protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: MAFG, also known as transcription factor MafG, belongs to the Maf family. Since they lack a putative transactivation domain, the small Mafs behave as transcriptional repressors when they dimerize among themselves. However, they seem to serve as transcriptional activators by dimerizing with other (usually larger) basic-zipper proteins and recruiting them to specific DNA-binding sites. Small Maf proteins heterodimerize with Fos and may act as competitive repressors of the NF-E2 transcription factor.
• Form: Liquid. 20mM Tris-HCl buffer (pH8.0) containing 40% glycerol, 0.15M NaCl, 1mM DTT
• Molecular Weight: 20.0 kDa (182aa), confirmed by MALDI-TOF
• Purity: > 90% by SDS - PAGE
• Concentration: 0.25 mg/ml (determined by Bradford assay)
• Sequences of amino acids: MGSSHHHHHH SSGLVPRGSHMTTPNKGNKA LKVKREPGEN GTSLTDEELV TMSVRELNQH LRGLSKEEIV QLKQRRRTLK NRGYAASCRV KRVTQKEELE KQKAELQQEV EKLASENASM KLELDALRSK YEALQTFART VARSPVAPAR GPLAAGLGPL VPGKVAATSV ITIVKSKTDA RS
• Storage: Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• Pathways: Factors involved in megakaryocyte development and platelet production; Hemostasis

Gene Information

• Gene Name: MAFG v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian) [ Homo sapiens ]
• Official Symbol: MAFG
• Synonyms: MAFG; hMAF; MGC13090; MGC20149; transcription factor MafG; basic leucine zipper transcription factor MafG; v-maf musculoaponeurotic fibrosarcoma oncogene homolog G (avian)
• Gene ID: 4097
• mRNA Refseq: NM_032711
• Protein Refseq: NP_116100
• MIM: 602020
• UniProt ID: O15525
• Chromosome Location: 17q25.3
• Function: sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity