Recombinant Human Vascular Endothelial Growth Factor C, His-tagged

• Cat.No.: VEGFC-615H
• Product Overview: The recombinant human protein contains N-terminal and C-terminal His-tags (167 aa, MW 18.772 kDa).

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Description: The recombinant VEGFC (Vascular Endothelial Growth Factor-C) lacks the N-terminal signal peptide and includes amino acids from T103 to R227 of Gene Bank U58111.
• Biological Activity: Activity of VEGFC is tested by the stimulation of VEGF-R3 phosphorylation in cells transfected with VEGF-R3. The expected ED50 is > 200 ng/ml.
• Molecular Weight: 18.772 kDa
• Form: Lyophilized without additives.
• Appearance: Lyophilized protein
• Endotoxin Level: <0.1 ng/μg
• Reconstitution: We recommend a quick spin followed by reconstitution in 0.1% acetic acid to a concentration of 0.1-1.0 mg/ml. The solution should be stored at -70°C.
• Purity: >90% by SDS-PAGE analyses.
• Storage: The lyophilized VEGFC is best-stored at -20°C. Reconstituted VEGFC should be stored in working aliquots at -70°C.
• Pathways: Bladder cancer; Cytokine-cytokine receptor interaction; Focal Adhesion; Focal adhesion; Formation of Platelet plug; Heart Development; Hemostasis; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; Response to elevated platelet cytosolic Ca2+; Signaling by VEGF; Signaling events mediated by VEGFR1 and VEGFR2; VEGF ligand-receptor interactions; VEGFR3 signaling in lymphatic endothelium; mTOR signaling pathway

Gene Information

• Gene Name: VEGFC vascular endothelial growth factor C [ Homo sapiens ]
• Official Symbol: VEGFC
• Synonyms: VEGFC; vascular endothelial growth factor C; RP; Flt4-L; VEGF-C; FLT4 ligand DHM; OTTHUMP00000218843; vascular endothelial growth factor-related protein; VRP; Flt4 ligand
• Gene ID: 7424
• mRNA Refseq: NM_005429
• Protein Refseq: NP_005420
• MIM: 601528
• UniProt ID: P4976
• Chromosome Location: 4q34.3
• Function: chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding