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Recombinant Human Vascular Endothelial Growth Factor C, His-tagged

Cat.No. : VEGFC-615H
Product Overview : The recombinant human protein contains N-terminal and C-terminal His-tags (167 aa, MW 18.772 kDa).
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  • Gene Information
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Cat. No. : VEGFC-615H
Description : The recombinant VEGFC (Vascular Endothelial Growth Factor-C) lacks the N-terminal signal peptide and includes amino acids from T103 to R227 of Gene Bank U58111.
Biological Activity : Activity of VEGFC is tested by the stimulation of VEGF-R3 phosphorylation in cells transfected with VEGF-R3. The expected ED50 is > 200 ng/ml.
Molecular Weight : 18.772 kDa
Source : E. coli
Species : Human
Form : Lyophilized without additives.
Appearance : Lyophilized protein
Endotoxin Level : <0.1 ng/μg
Reconstitution : We recommend a quick spin followed by reconstitution in 0.1% acetic acid to a concentration of 0.1-1.0 mg/ml. The solution should be stored at -70°C.
Purity : >90% by SDS-PAGE analyses.
Storage : The lyophilized VEGFC is best-stored at -20°C. Reconstituted VEGFC should be stored in working aliquots at -70°C.
Pathways : Bladder cancer; Cytokine-cytokine receptor interaction; Focal Adhesion; Focal adhesion; Formation of Platelet plug; Heart Development; Hemostasis; Pancreatic cancer; Pathways in cancer; Renal cell carcinoma; Response to elevated platelet cytosolic Ca2+; Signaling by VEGF; Signaling events mediated by VEGFR1 and VEGFR2; VEGF ligand-receptor interactions; VEGFR3 signaling in lymphatic endothelium; mTOR signaling pathway
Gene Name : VEGFC vascular endothelial growth factor C [ Homo sapiens ]
Official Symbol : VEGFC
Synonyms : VEGFC; vascular endothelial growth factor C; RP; Flt4-L; VEGF-C; FLT4 ligand DHM; OTTHUMP00000218843; vascular endothelial growth factor-related protein; VRP; Flt4 ligand
Gene ID : 7424
mRNA Refseq : NM_005429
Protein Refseq : NP_005420
MIM : 601528
UniProt ID : P4976
Chromosome Location : 4q34.3
Function : chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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