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Recombinant Human VEGFC protein, His-tagged

Cat.No.: VEGFC-29H
Product Overview: Recombinant human VEGFC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.
Description: VEGFC, also known as vascular endothelial growth factor C, is a member of the VEGF family. This growth factors play key roles in the physiology and pathology of many aspects of the cardiovascular system including hematopoiesis, angiogenesis and vascular permeability. Traces of VEGFC are also detected in brain, liver, thymus, skeletal muscles, spleen, prostate, testis and colon. Unlike other VEGF family members, VEGFC expression is not regulated by hypoxia.
Source: Insect cells
Species: Human
Tag: His tag
Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol.
Molecular Mass: 14.2kDa (125aa)18-28KDa (SDS-PAGE under reducing conditions.)
AA Sequence: ADPAHYNTEI LKSIDNEWRK TQCMPREVCI DVGKEFGVAT NTFFKPPCVS VYRCGGCCNS EGLQCMNTST SYLSKTLFEI TVPLSQGPKP VTISFANHTS CRCMSKLDVY RQVHSIIRRH HHHHH
Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
Purity: >90% by SDS - PAGE
Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
Concentration: 0.5mg/ml (determined by Absorbance at 280nm)
Gene Name: VEGFC vascular endothelial growth factor C [ Homo sapiens ]
Official Symbol: VEGFC
Synonyms: VEGFC; VRP; VEGF-C; FLT4 ligand DHM; Flt4-L
Gene ID: 7424
mRNA Refseq: NM_005429
Protein Refseq: NP_005420
MIM: 601528
UniProt ID: P49767
Chromosome Location: 4q34.3
Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem;
Function: chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding;

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Optional requirements on this protein    +Expand
C-fusion    N-fusion   Non-tagged
His    GST   Fc   Others
<1.0 eu/μg    <0.1 eu/μg   <0.01 eu/μg   Not required
Monomer Isolation    Dimer Isolation    Not required
>80% by SDS-PAGE    >90% by SDS-PAGE   >95% by SDS-PAGE   Others

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