Recombinant Human VEGFC protein, His-tagged

• Cat.No.: VEGFC-29H
• Product Overview: Recombinant human VEGFC, fused to His-tag at C-terminus, was expressed in insect cell and purified by using conventional chromatography techniques.

Specification

• Description: VEGFC, also known as vascular endothelial growth factor C, is a member of the VEGF family. This growth factors play key roles in the physiology and pathology of many aspects of the cardiovascular system including hematopoiesis, angiogenesis and vascular permeability. Traces of VEGFC are also detected in brain, liver, thymus, skeletal muscles, spleen, prostate, testis and colon. Unlike other VEGF family members, VEGFC expression is not regulated by hypoxia.
• Source: Insect cells
• Species: Human
• Tag: His tag
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 20% glycerol.
• Molecular Mass: 14.2kDa (125aa)18-28KDa (SDS-PAGE under reducing conditions.)
• AA Sequence: ADPAHYNTEI LKSIDNEWRK TQCMPREVCI DVGKEFGVAT NTFFKPPCVS VYRCGGCCNS EGLQCMNTST SYLSKTLFEI TVPLSQGPKP VTISFANHTS CRCMSKLDVY RQVHSIIRRH HHHHH
• Endotoxin: < 1.0 EU per 1 microgram of protein (determined by LAL method)
• Purity: >90% by SDS - PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 0.5mg/ml (determined by Absorbance at 280nm)

Gene Information

• Gene Name: VEGFC vascular endothelial growth factor C [ Homo sapiens ]
• Official Symbol: VEGFC
• Synonyms: VEGFC; VRP; VEGF-C; FLT4 ligand DHM; Flt4-L
• Gene ID: 7424
• mRNA Refseq: NM_005429
• Protein Refseq: NP_005420
• MIM: 601528
• UniProt ID: P49767
• Chromosome Location: 4q34.3
• Pathway: Bladder cancer, organism-specific biosystem; Bladder cancer, conserved biosystem; Cytokine-cytokine receptor interaction, organism-specific biosystem; Cytokine-cytokine receptor interaction, conserved biosystem; Focal Adhesion, organism-specific biosystem; Focal adhesion, organism-specific biosystem; Focal adhesion, conserved biosystem
• Function: chemoattractant activity; growth factor activity; protein binding; vascular endothelial growth factor receptor 3 binding