Recombinant Human VPS33B Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : VPS33B-5610H
Product Overview : VPS33B MS Standard C13 and N15-labeled recombinant protein (NP_061138) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : Vesicle mediated protein sorting plays an important role in segregation of intracellular molecules into distinct organelles. Genetic studies in yeast have identified more than 40 vacuolar protein sorting (VPS) genes involved in vesicle transport to vacuoles. This gene is a member of the Sec-1 domain family, and encodes the human ortholog of rat Vps33b which is homologous to the yeast class C Vps33 protein. The mammalian class C vacuolar protein sorting proteins are predominantly associated with late endosomes/lysosomes, and like their yeast counterparts, may mediate vesicle trafficking steps in the endosome/lysosome pathway. Mutations in this gene are associated with arthrogryposis-renal dysfunction-cholestasis syndrome. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 70.6 kDa
AA Sequence : MAFPHRPDAPELPDFSMLKRLARDQ LIYLLEQLPGKKDLFIEADLMSPLD RIANVSILKQHEVDKLYKVENKPAL SSNEQLCFLVRPRIKNMRYIASLVN ADKLAGRTRKYKVIFSPQKFYACEM VLEEEGIYGDVSCDEWAFSLLPLDV DLLSMELPEFFRDYFLEGDQRWINT VAQALHLLSTLYGPFPNCYGIGRCA KMAYELWRNLEEEEDGETKGRRPEI GHIFLLDRDVDFVTALCSQVVYEGL VDDTFRIKCGSVDFGPEVTSSDKSL KVLLNAEDKVFNEIRNEHFSNVFGF LSQKARNLQAQYDRRRGMDIKQMKN FVSQELKGLKQEHRLLSLHIGACES IMKKKTKQDFQELIKTEHALLEGFN IRESTSYIEEHIDRQVSPIESLRLM CLLSITENGLIPKDYRSLKTQYLQS YGPEHLLTFSNLRRAGLLTEQAPGD TLTAVESKVSKLVTDKAAGKITDAF SSLAKRSNFRAISKKLNLIPRVDGE YDLKVPRDMAYVFSGAYVPLSCRII EQVLERRSWQGLDEVVRLLNCSDFA FTDMTKEDKASSESLRLILVVFLGG CTFSEISALRFLGREKGYRFIFLTT AVTNSARLMEAMSEVKATRTRPLEQ KLISEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : VPS33B VPS33B late endosome and lysosome associated [ Homo sapiens (human) ]
Official Symbol : VPS33B
Synonyms : VPS33B; vacuolar protein sorting 33 homolog B (yeast); vacuolar protein sorting 33B (yeast homolog); vacuolar protein sorting-associated protein 33B; FLJ14848; hVPS33B; vacuolar protein sorting 33B;
Gene ID : 26276
mRNA Refseq : NM_018668
Protein Refseq : NP_061138
MIM : 608552
UniProt ID : Q9H267

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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