Recombinant Human VPS72 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : VPS72-5247H
Product Overview : VPS72 MS Standard C13 and N15-labeled recombinant protein (NP_005988) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : The protein encoded by this gene is a shared subunit of two multi-component complexes, the histone acetyltransferase complex TRRAP/TIP60 as well as the chromatin remodeling SRCAP-containing complex. The TRRAP/TIP60 complex acetylates nucleosomal histones important for transcriptional regulation, double strand DNA break repair and apoptosis. The SRCAP-containing complex catalyzes the exchange of histone H2A with the histone variant Htz1 (H2AFZ) into nucleosomes. This protein may be responsible for binding H2AFZ, which has a role in chromosome segregation. This protein may also have a role in regulating long-term hematopoietic stem cell activity. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 40.6 kDa
AA Sequence : MSLAGGRAPRKTAGNRLSGLLEAEE EDEFYQTTYGGFTEESGDDEYQGDQ SDTEDEVDSDFDIDEGDEPSSDGEA EEPRRKRRVVTKAYKEPLKSLRPRK VNTPAGSSQKAREEKALLPLELQDD GSDSRKSMRQSTAEHTRQTFLRVQE RQGQSRRRKGPHCERPLTQEELLRE AKITEELNLRSLETYERLEADKKKQ VHKKRKCPGPIITYHSVTVPLVGEP GPKEENVDIEGLDPAPSVSALTPHA GTGPVNPPARCSRTFITFSDDATFE EWFPQGRPPKVPVREVCPVTHRPAL YRDPVTDIPYATARAFKIIREAYKK YITAHGLPPTASALGPGPPPPEPLP GSGPRALRQKIVIKTRTRPLEQKLI SEEDLAANDILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : VPS72 vacuolar protein sorting 72 homolog [ Homo sapiens (human) ]
Official Symbol : VPS72
Synonyms : VPS72; vacuolar protein sorting 72 homolog (S. cerevisiae); TCFL1, transcription factor like 1, vacuolar protein sorting 72 (yeast); vacuolar protein sorting-associated protein 72 homolog; Swc2; YL 1; YL1; protein YL-1; transcription factor-like 1 (YL-1); CFL1; YL-1; TCFL1;
Gene ID : 6944
mRNA Refseq : NM_005997
Protein Refseq : NP_005988
MIM : 600607
UniProt ID : Q15906

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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