Recombinant Human VTCN1 protein, His & GST-tagged

• Cat.No.: VTCN1-1740H
• Product Overview: Recombinant Human VTCN1 aa. (Pro153~Thr241 (Accession # Q7Z7D3)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Description: This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: E. coli
• Species: Human
• Tag: His&GST
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 42.3kDa
• Protein length: Pro153~Thr241
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >95%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% sucrose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 5.7

Gene Information

• Gene Name: VTCN1 V-set domain containing T-cell activation inhibitor 1 [ Homo sapiens (human) ]
• Official Symbol: VTCN1
• Synonyms: VTCN1; V-set domain containing T-cell activation inhibitor 1; B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291; V-set domain-containing T-cell activation inhibitor 1; B7 family member, H4; B7 homolog 4; B7 superfamily member 1; T cell costimulatory molecule B7x; immune costimulatory protein B7-H4
• Gene ID: 79679
• mRNA Refseq: NM_001253849.1
• Protein Refseq: NP_001240778.1
• UniProt ID: Q7Z7D3