Recombinant Human VTI1A Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: VTI1A-5950H
• Product Overview: VTI1A MS Standard C13 and N15-labeled recombinant protein (NP_660207) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a member of the family of soluble N-ethylmaleimide-sensitive fusion protein-attachment protein receptors (SNAREs) that function in intracellular trafficking. This family member is involved in vesicular transport between endosomes and the trans-Golgi network. It is a vesicle-associated SNARE (v-SNARE) that interacts with target membrane SNAREs (t-SNAREs). Polymorphisms in this gene have been associated with binocular function, and also with susceptibility to colorectal and lung cancers. A recurrent rearrangement has been found between this gene and the transcription factor 7-like 2 (TCF7L2) gene in colorectal cancers. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 25 kDa
• AA Sequence: MSSDFEGYEQDFAVLTAEITSKIAR VPRLPPDEKKQMVANVEKQLEEAKE LLEQMDLEVREIPPQSRGMYSNRMR SYKQEMGKLETDFKRSRIAYSDEVR NELLGDDGNSSENQRAHLLDNTERL ERSSRRLEAGYQIAVETEQIGQEML ENLSHDREKIQRARERLRETDANLG KSSRILTGMLRRIIQNRILLVILGI IVVITILMAITFSVRRHTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: VTI1A vesicle transport through interaction with t-SNAREs 1A [ Homo sapiens (human) ]
• Official Symbol: VTI1A
• Synonyms: VTI1A; vesicle transport through interaction with t-SNAREs homolog 1A (yeast); vesicle transport through interaction with t-SNAREs homolog 1A; MVti1; Vti1 rp2; Vti1a; SNARE Vti1a-beta protein; vesicle transport v-SNARE protein Vti1-like 2; VTI1RP2; Vti1-rp2
• Gene ID: 143187
• mRNA Refseq: NM_145206
• Protein Refseq: NP_660207
• MIM: 614316
• UniProt ID: Q96AJ9