Recombinant Human WARS Protein (Phe247-Lys458), His tagged

• Cat.No.: WARS-6570H
• Product Overview: Recombinant human WARS (Phe247-Lys458) fused with His tag was expressed in E. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: His
• Protein Length: Phe247-Lys458
• Description: Isoform 1, isoform 2 and T1-TrpRS have aminoacylation activity while T2-TrpRS lacks it. Isoform 2, T1-TrpRS and T2-TrpRS possess angiostatic activity whereas isoform 1 lacks it. T2-TrpRS inhibits fluid shear stress-activated responses of endothelial cells. Regulates ERK, Akt, and eNOS activation pathways that are associated with angiogenesis, cytoskeletal reorganization and shear stress-responsive gene expression.
• Form: Lyophilized powder/frozen liquid
• Molecular Mass: 24.04 kDa
• Purity: > 90 % as determined by SDS-PAGE
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS, pH 7.5 or lyophilized from PBS, pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: WARS tryptophanyl-tRNA synthetase [ Homo sapiens (human) ]
• Official Symbol: WARS
• Synonyms: WARS; tryptophanyl-tRNA synthetase; IFI53; tryptophan--tRNA ligase, cytoplasmic; IFP53; tryptophan tRNA ligase 1; cytoplasmic; hWRS; trpRS; interferon-induced protein 53; tryptophan tRNA ligase 1, cytoplasmic; GAMMA-2
• Gene ID: 7453
• mRNA Refseq: NM_004184
• Protein Refseq: NP_004175
• MIM: 191050
• UniProt ID: P23381