Active Recombinant Human WFIKKN2 protein

• Cat.No.: WFIKKN2-028H
• Product Overview: Recombinant Human WFIKKN2 was expressed in CHO cells.

Specification

• Description: The WFIKKN1 protein contains a WAP domain, follistatin domain, immunoglobulin domain, two tandem Kunitz domains, and an NTR domain. This gene encodes a WFIKKN1-related protein which has the same domain organization as the WFIKKN1 protein. The WAP-type, follistatin type, Kunitz-type, and NTR-type protease inhibitory domains may control the action of multiple types of proteases.
• Source: CHO cells
• Species: Human
• Form: Lyophilized from a 0.2 µM filtered solution of 20mM phosphate buffer,100mM NaCl, pH 7.2
• Bio-activity: Determined by its ability to inhibit human Myostatin (GDF-8) activity in MCP-11 cells. The ED50 for this effect is 0.0025-0.0040 ug/ml in the presence of 5ng/ml of human Myostatin (GDF-8).
• Molecular Mass: 63.8 kDa
• AA Sequence: LPPIRYSHAGICPNDMNPNLWVDAQ STCRRECETDQECETYEKCCPNVCG TKSCVAARYMDVKGKKGPVGMPKEA TCDHFMCLQQGSECDIWDGQPVCKC KDRCEKEPSFTCASDGLTYYNRCYM DAEACSKGITLAVVTCRYHFTWPNT SPPPPETTMHPTTASPETPELDMAA PALLNNPVHQSVTMGETVSFLCDVV GRPRPEITWEKQLEDRENVVMRPNH VRGNVVVTNIAQLVIYNAQLQDAGI YTCTARNVAGVLRADFPLSVVRGHQ AAATSESSPNGTAFPAAECLKPPDS EDCGEEQTRWHFDAQANNCLTFTFG HCHRNLNHFETYEACMLACMSGPLA ACSLPALQGPCKAYAPRWAYNSQTG QCQSFVYGGCEGNGNNFESREACEE SCPFPRGNQRCRACKPRQKLVTSFC RSDFVILGRVSELTEEPDSGRALVT VDEVLKDEKMGLKFLGQEPLEVTLL HVDWACPCPNVTVSEMPLIIMGEVD GGMAMLRPDSFVGASSARRVRKLRE VMHKKTCDVLKEFLGLH
• Endotoxin: Endotoxin level is <0.1 ng/µg of protein (<1EU/µg).
• Purity: >95% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: Resuspend the protein in the desired concentration in proper buffer

Gene Information

• Gene Name: WFIKKN2 WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2 [ Homo sapiens ]
• Official Symbol: WFIKKN2
• Synonyms: WFIKKN2; WAP, follistatin/kazal, immunoglobulin, kunitz and netrin domain containing 2; WAP, kazal, immunoglobulin, kunitz and NTR domain-containing protein 2; WFIKKNRP; WFIKKN-related protein; multivalent protease inhibitor protein; WAP, FS, Ig, two KU and NTR module related protein; growth and differentiation factor-associated serum protein 1; WAP, follistatin, immunoglobulin, kunitz and NTR domain-containing-related protein; GASP-1; hGASP-1
• Gene ID: 124857
• mRNA Refseq: NM_175575
• Protein Refseq: NP_783165
• MIM: 610895
• UniProt ID: Q8TEU8