Recombinant Human XIAP, His-tagged

• Cat.No.: XIAP-410H
• Product Overview: A DNA sequence encoding the human BIR3 domain of XIAP (P29218-1) (Asn252-Thr356) was expressed with a polyhistidine tag at the N-terminus.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: Lyophilized from sterile PBS, pH7.4.
• Molecular Mass: The recombinant human BIR3 domain of XIAP consists of 123 amino acids and predicts a molecular mass of 14.3 KDa. It migrates as an approximately 14.8 KDa band in SDS-PAGE under reducing conditions.
• Protein length: Asn252-Thr356
• Endotoxin: < 1.0 eu per μg of the protein as determined by the LAL method.
• Purity: >95 % as determined by SDS-PAGE
• Stability: Samples are stable for up to twelve months from date of receipt at -70℃
• Storage: Store it under sterile conditions at -70℃. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: Hardcopy of COA with reconstitution instruction is sent along with the products.

Gene Information

• Gene Name: XIAP X-linked inhibitor of apoptosis [ Homo sapiens ]
• Official Symbol: XIAP
• Synonyms: XIAP; X-linked inhibitor of apoptosis; API3, baculoviral IAP repeat containing 4 , BIRC4; baculoviral IAP repeat-containing protein 4; hILP; X-linked IAP; IAP-like protein; E3 ubiquitin-protein ligase XIAP; inhibitor of apoptosis protein 3; baculoviral IAP repeat-containing 4; X-linked inhibitor of apoptosis protein; API3; ILP1; MIHA; XLP2; BIRC4; IAP-3; hIAP3; hIAP-3; FLJ26913
• Gene ID: 331
• mRNA Refseq: NM_001167
• Protein Refseq: NP_001158
• MIM: 300079
• UniProt ID: P98170
• Chromosome Location: Xq25
• Pathway: Apoptosis, organism-specific biosystem; Apoptosis, organism-specific biosystem; Apoptosis, conserved biosystem; Apoptosis, organism-specific biosystem; Apoptotic factor-mediated response, organism-specific biosystem; BMP receptor signaling, organism-specific biosystem; Caspase cascade in apoptosis, organism-specific biosystem
• Function: cysteine-type endopeptidase inhibitor activity involved in apoptotic process; ligase activity; metal ion binding; peptidase inhibitor activity; protein binding; ubiquitin-protein ligase activity; zinc ion binding