| Description : |
The protein encoded by this gene belongs to the family of X-pro-aminopeptidases that utilize a metal cofactor, and remove the N-terminal amino acid from peptides with a proline residue in the penultimate position. This protein has been shown to localize to the mitochondria of renal cells, and have a role in ciliary function. Mutations in this gene are associated with nephronophthisis-like nephropathy-1. Alternatively spliced transcript variants encoding different isoforms have been noted for this gene, however, expression of some of these isoforms in vivo is not known. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
57.1 kDa |
| AA Sequence : |
MPWLLSAPKLVPAVANVRGLSGCML CSQRRYSLQPVPERRIPNRYLGQPS PFTHPHLLRPGEVTPGLSQVEYALR RHKLMSLIQKEAQGQSGTDQTVVVL SNPTYYMSNDIPYTFHQDNNFLYLC GFQEPDSILVLQSLPGKQLPSHKAI LFVPRRDPSRELWDGPRSGTDGAIA LTGVDEAYTLEEFQHLLPKMKAETN MVWYDWMRPSHAQLHSDYMQPLTEA KAKSKNKVRGVQQLIQRLRLIKSPA EIERMQIAGKLTSQAFIETMFTSKA PVEEAFLYAKFEFECRARGADILAY PPVVAGGNRSNTLHYVKNNQLIKDG EMVLLDGGCESSCYVSDITRTWPVN GRFTAPQAELYEAVLEIQRDCLALC FPGTSLENIYSMMLTLIGQKLKDLG IMKNIKENNAFKAARKYCPHHVGHY LGMDVHDTPDMPRSLPLQPGMVITI EPGIYIPEDDKDAPEKFRGLGVRIE DDVVVTQDSPFILSADCPKEMNDIE QICSQASTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
