Description : |
The protein encoded by this gene is a member of the importin-beta family. Members of this family are regulated by the GTPase Ran to mediate transport of cargo across the nuclear envelope. This protein has been shown to mediate nuclear export of profilin-actin complexes. A pseudogene of this gene is located on the long arm of chromosome 14. Alternative splicing results in multiple transcript variants that encode different protein isoforms. |
Source : |
E. coli |
Species : |
Human |
Tag : |
His & T7 |
Form : |
Freeze-dried powder |
Molecular Mass : |
Predicted Molecular Mass: 34.3kDa |
Protein length : |
Ala2~Leu271 (Accession # Q96QU8) |
Endotoxin : |
<1.0EU per 1ug (determined by the LAL method) |
Purity : |
>90% |
Applications : |
SDS-PAGE; WB; ELISA; IP. |
Stability : |
The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition. |
Storage : |
Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months. |
Storage buffer : |
Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative. |
Reconstitution : |
Reconstitute in sterile ddH2O. |
Isoelectric Point : |
5.3 |