Recombinant Human XRCC1 Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | XRCC1-4675H |
Product Overview : | XRCC1 MS Standard C13 and N15-labeled recombinant protein (NP_006288) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 69.5 kDa |
AA Sequence : | MPEIRLRHVVSCSSQDSTHCAENLL KADTYRKWRAAKAGEKTISVVLQLE KEEQIHSVDIGNDGSAFVEVLVGSS AGGAGEQDYEVLLVTSSFMSPSESR SGSNPNRVRMFGPDKLVRAAAEKRW DRVKIVCSQPYSKDSPFGLSFVRFH SPPDKDEAEAPSQKVTVTKLGQFRV KEEDESANSLRPGALFFSRINKTSP VTASDPAGPSYAAATLQASSAASSA SPVSRAIGSTSKPQESPKGKRKLDL NQEEKKTPSKPPAQLSPSVPKRPKL PAPTRTPATAPVPARAQGAVTGKPR GEGTEPRRPRAGPEELGKILQGVVV VLSGFQNPFRSELRDKALELGAKYR PDWTRDSTHLICAFANTPKYSQVLG LGGRIVRKEWVLDCHRMRRRLPSQR YLMAGPGSSSEEDEASHSGGSGDEA PKLPQKQPQTKTKPTQAAGPSSPQK PPTPEETKAASPVLQEDIDIEGVQS EGQDNGAEDSGDTEDELRRVAEQKE HRLPPGQEENGEDPYAGSTDENTDS EEHQEPPDLPVPELPDFFQGKHFFL YGEFPGDERRKLIRYVTAFNGELED YMSDRVQFVITAQEWDPSFEEALMD NPSLAFVRPRWIYSCNEKQKLLPHQ LYGVVPQATRTRPLEQKLISEEDLA ANDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 [ Homo sapiens (human) ] |
Official Symbol : | XRCC1 |
Synonyms : | XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; RCC; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1; X-ray-repair, complementing defective, repair in Chinese hamster; |
Gene ID : | 7515 |
mRNA Refseq : | NM_006297 |
Protein Refseq : | NP_006288 |
MIM : | 194360 |
UniProt ID : | P18887 |
Products Types
◆ Recombinant Protein | ||
XRCC1-1500H | Recombinant Human XRCC1 Protein, MYC/DDK-tagged | +Inquiry |
XRCC1-2369H | Recombinant Human XRCC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
XRCC1-596H | Recombinant Human XRCC1 Protein, His-tagged | +Inquiry |
XRCC1-6276R | Recombinant Rat XRCC1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Xrcc1-597M | Recombinant Mouse Xrcc1 Protein, His-tagged | +Inquiry |
◆ Lysates | ||
XRCC1-258HCL | Recombinant Human XRCC1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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