| Cat.No. : |
XRCC1-1500H |
| Product Overview : |
Recombinant Human XRCC1 Protein was expressed in human HEK293 cells with C-terminal MYC/DDK-tag. |
| Description : |
The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
MYC/DDK |
| Form : |
Liquid |
| Molecular Mass : |
69.3 kDa |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
>50 ug/mL as determined by microplate BCA method |
| Storage Buffer : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
