Recombinant Human XRCC1 Protein, MYC/DDK-tagged


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Recombinant Human XRCC1 Protein, MYC/DDK-tagged

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Cat.No. : XRCC1-1500H
Product Overview : Recombinant Human XRCC1 Protein was expressed in human HEK293 cells with C-terminal MYC/DDK-tag.
Description : The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
Source : HEK293
Species : Human
Form : Liquid
Molecular Mass : 69.3 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Storage Buffer : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Gene Name : XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 [ Homo sapiens ]
Official Symbol : XRCC1
Synonyms : XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; RCC; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1; X-ray-repair, complementing defective, repair in Chinese hamster;
Gene ID : 7515
mRNA Refseq : NM_006297
Protein Refseq : NP_006288
MIM : 194360
UniProt ID : P18887

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