Recombinant Human XRCC1 Protein, MYC/DDK-tagged
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Cat.No. : | XRCC1-1500H |
Product Overview : | Recombinant Human XRCC1 Protein was expressed in human HEK293 cells with C-terminal MYC/DDK-tag. |
Description : | The protein encoded by this gene is involved in the efficient repair of DNA single-strand breaks formed by exposure to ionizing radiation and alkylating agents. This protein interacts with DNA ligase III, polymerase beta and poly (ADP-ribose) polymerase to participate in the base excision repair pathway. It may play a role in DNA processing during meiogenesis and recombination in germ cells. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity. |
Source : | HEK293 |
Species : | Human |
Tag : | MYC/DDK |
Form : | Liquid |
Molecular Mass : | 69.3 kDa |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Concentration : | >50 ug/mL as determined by microplate BCA method |
Storage Buffer : | 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
Gene Name : | XRCC1 X-ray repair complementing defective repair in Chinese hamster cells 1 [ Homo sapiens ] |
Official Symbol : | XRCC1 |
Synonyms : | XRCC1; X-ray repair complementing defective repair in Chinese hamster cells 1; RCC; DNA repair protein XRCC1; X-ray repair cross-complementing protein 1; X-ray-repair, complementing defective, repair in Chinese hamster; |
Gene ID : | 7515 |
mRNA Refseq : | NM_006297 |
Protein Refseq : | NP_006288 |
MIM : | 194360 |
UniProt ID : | P18887 |
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◆ Lysates
XRCC1-258HCL | Recombinant Human XRCC1 293 Cell Lysate | +Inquiry |
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