Recombinant Human XRCC3, T7-tagged

• Cat.No.: XRCC3-3057H
• Product Overview: Recombinant Human XRCC3 (1-346 aa) is expressed inE.Coliwith a T7 tag at N-terminus.

Specification

• Species: Human
• Source: E.coli
• Tag: T7
• Protein Length: 1-346 a.a.
• Description: This gene encodes a member of the RecA/Rad51-related protein family that participates in homologous recombination to maintain chromosome stability and repair DNA damage. This gene functionally complements Chinese hamster irs1SF, a repair-deficient mutant that exhibits hypersensitivity to a number of different DNA-damaging agents and is chromosomally unstable. A rare microsatellite polymorphism in this gene is associated with cancer in patients of varying radiosensitivity.
• MW: 37850 Da.
• Purity: 90%.
• Formulation: 10 mM Tris. pH 8.0. 0.1% Triton X-100.0.002% NaN3. 10mM DTT.
• Application: MS. SDS.

Gene Information

• Gene Name: XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 [ Homo sapiens ]
• Synonyms: XRCC3; X-ray repair complementing defective repair in Chinese hamster cells 3; DNA repair protein XRCC3; RAD51-like; X-ray repair cross-complementing protein 3; CMM6
• Gene ID: 7517
• mRNA Refseq: NM_001100118
• Protein Refseq: NP_001093588
• MIM: 600675
• UniProt ID: O43542
• Chromosome Location: 14q32.3
• Pathway: Homologous recombination
• Function: ATP binding; DNA binding; DNA-dependent ATPase activity; nucleotide binding