Recombinant Human YWHAB Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: YWHAB-1959H
• Product Overview: YWHAB MS Standard C13 and N15-labeled recombinant protein (NP_003395) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 28.1 kDa
• AA Sequence: MTMDKSELVQKAKLAEQAERYDDMA AAMKAVTEQGHELSNEERNLLSVAY KNVVGARRSSWRVISSIEQKTERNE KKQQMGKEYREKIEAELQDICNDVL ELLDKYLIPNATQPESKVFYLKMKG DYFRYLSEVASGDNKQTTVSNSQQA YQEAFEISKKEMQPTHPIRLGLALN FSVFYYEILNSPEKACSLAKTAFDE AIAELDTLNEESYKDSTLIMQLLRD NLTLWTSENQGDEGDAGEGENTRTR PLEQKLISEEDLAANDILDYKDDDD KV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta [ Homo sapiens (human) ]
• Official Symbol: YWHAB
• Synonyms: YWHAB; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide; tyrosine 3 monooxygenase/tryptophan 5 monooxygenase activation protein, alpha polypeptide, YWHAA; 14-3-3 protein beta/alpha; 14 3 3 alpha; 14 3 3 beta; 14-3-3 alpha; protein 1054; brain protein 14-3-3, beta isoform; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; HS1; GW128; YWHAA; KCIP-1
• Gene ID: 7529
• mRNA Refseq: NM_003404
• Protein Refseq: NP_003395
• MIM: 601289
• UniProt ID: P31946