Recombinant Human ZFAND5 Protein (A2-I213), Tag Free

• Cat.No.: ZFAND5-0592H
• Product Overview: Recombinant Human (GG)-ZFAND5(A2-I213 end) Protein was expressed in Insect cell.

Specification

• Description: Involved in protein degradation via the ubiquitin-proteasome system. May act by anchoring ubiquitinated proteins to the proteasome. Plays a role in ubiquitin-mediated protein degradation during muscle atrophy. Plays a role in the regulation of NF-kappa-B activation and apoptosis. Inhibits NF-kappa-B activation triggered by overexpression of RIPK1 and TRAF6 but not of RELA. Inhibits also tumor necrosis factor (TNF), IL-1 and TLR4-induced NF-kappa-B activation in a dose-dependent manner. Overexpression sensitizes cells to TNF-induced apoptosis. Is a potent inhibitory factor for osteoclast differentiation.
• Source: Insect cell
• Species: Human
• Tag: No tag
• Form: Liquid
• Protein Length: A2-I213
• Endotoxin: < 0.01 EU per μg of the protein
• Purity: 90%
• Stability: Samples are stable for up to twelve months from date of receipt at -20 to -80 centigrade.
• Storage: Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Storage Buffer: Supplied as sterile 50 mM Tris-HCl (pH7.5), 200 mM NaCl, 20% glycerol
• Shipping: It is shipped out with blue ice.

Gene Information

• Gene Name: ZFAND5 zinc finger, AN1-type domain 5 [ Homo sapiens (human) ]
• Official Symbol: ZFAND5
• Synonyms: ZFAND5; zinc finger, AN1-type domain 5; ZA20D2, zinc finger protein 216, zinc finger, A20 domain containing 2, ZNF216; AN1-type zinc finger protein 5; ZFAND5A; zinc finger protein 216; zinc finger, A20 domain containing 2; zinc finger A20 domain-containing protein 2; ZA20D2; ZNF216
• Gene ID: 7763
• mRNA Refseq: NM_001102420
• Protein Refseq: NP_001095890
• MIM: 604761
• UniProt ID: O76080