Recombinant Influenza A H5N1 HA, His tagged
Cat.No. : | HA-736I |
Product Overview : | Recombinant Influenza A H5N1 HA (A/Turkey/1/2005 (H5N1)) (ABD73284.1) extracellular domain hemagglutinin (Met 1-Gln 531) with cleavage site mutated (GERRRKKR → TETR, HA1+HA2, uncleaved), fused with a C-terminal polyhistidine tag, was produced in Human Cel |
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Source : | Human Cells |
Species : | Influenza A H5N1 |
Tag : | His |
Form : | Lyophilized from sterile PBS, pH 7.4 |
Molecular Mass : | The secreted recombinant Influenza A virus (A//Turkey/1/2005 (H5N1) HA (mutated) comprises 522 amino acids with the predicted molecular mass of 59 kDa. As a result of glycosylation, it migrates as an approximately 65-70 kDa band in SDS-PAGE under reducing conditions. |
Endotoxin : | < 1.0 eu per μg of the protein as determined by the LAL method. |
Stability : | Samples are stable for up to twelve months from date of receipt at -70oC. |
Storage : | Store it under sterile conditions at -20oC~-70oC. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Reconstitution : | It is recommended that sterile water be added to the vial to prepare a stock solution. Centrifuge the vial at 4℃ before opening to recover the entire contents. |
Protein length : | Met1-Gln531 |
Publication : |
Incorporation of Macromolecules into α-Lactose Monohydrate Crystals (2016)
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Gene Name : | HA hemagglutinin [ Influenza A virus (A/goose/Guangdong/1/1996(H5N1)) ] |
Official Symbol : | HA |
Gene ID : | 3654620 |
Protein Refseq : | YP_308669 |
UniProt ID : | Q9Q0U6 |
Products Types
◆ Lysates | ||
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HA-2668HCL | Recombinant H5N1 HA cell lysate | +Inquiry |
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Not For Human Consumption!
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Customer Reviews (2)
Write a reviewThe transport process does not affect the protein quality, and the stability is good.
Higher solubility makes it easy to prepare the desired concentration.
Q&As (6)
Ask a questionHA protein is a glycoprotein that contains thousands of carbohydrates and an amino acid chain consisting of 566 amino acid residues. The structure of HA protein has triple symmetry, consisting of three monomers that form a spiral.
Genetic variants in the HA protein may affect the development and production of influenza vaccines. Because HA protein is an important component of influenza viruses, different subtypes or variants of HA protein may require different vaccines to prepare.
This protein is one of the key factors in the replication process of influenza viruses. When a virus infects a host cell, the receptor-binding region of the HA protein binds to the receptor on the cell surface, allowing the virus to invade the host cell and replicate.
There are currently 18 known HA subtypes of influenza viruses, H1-H18. Among them, the H1, H2, H3, H5, H7, and H9 subtypes are associated with human viruses, while other subtypes are generally associated with animal viruses.
The main physiological function of HA protein is to bind to host cells and mediate the entry of influenza viruses into host cells. It contains specific regions that bind glycoprotein receptors that allow the influenza virus to adhere to them. This is an important link that allows the virus to stably bind and enter the cell.
HA protein is widely used in viral research and drug development. Researchers can use HA proteins to test drugs such as influenza virus activators, antibodies and vaccines, and HA proteins are also widely used to develop novel immunoassays and treatments.
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