Recombinant MERS-CoV S Protein (Glu11-Leu220), Tag Free tagged
Cat.No. : | S-5396M |
Product Overview : | Recombinant MERS-CoV S/Spike glycoprotein (RBD) (Glu11-Leu220) without tag was expressed in Mammalian cells. |
- Specification
- Gene Information
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Description : | Spike protein S1: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection. Spike protein S2: Acts as a viral fusion peptide which is unmasked following S2 cleavage occurring upon virus endocytosis. Spike protein S2: mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes. |
Source : | Mammalian cells |
Species : | MERS-CoV |
Tag : | Tag Free |
Form : | Lyophilized powder/frozen liquid |
Molecular Mass : | 25.51 kDa |
Protein Length : | Glu11-Leu220 |
Purity : | >90% as determined by SDS-PAGE. |
Notes : | For research use only. |
Storage : | Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt. |
Storage Buffer : | Supplied as solution form in PBS pH 7.4. |
Reconstitution : | Reconstitute in sterile water for a stock solution. |
Shipping : | They are shipped out with dry ice/blue ice unless customers require otherwise. |
Gene Name : | S spike protein [ Middle East respiratory syndrome-related coronavirus ] |
Official Symbol : | S |
Synonyms : | S; spike protein; surface glycoprotein |
Gene ID : | 14254594 |
Protein Refseq : | YP_009047204 |
UniProt ID : | A0A499Q7I9 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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