Recombinant Monkey NPR1 Protein, His-tagged

• Cat.No.: NPR1-11128M
• Product Overview: Cynomolgus NPR1 Protein, His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 33 - Glu 473 (Accession # XP_005541810.1). This protein carries a polyhistidine tag at the C-terminus. Predicted N-terminus: Gly 33. The protein is designed as a dimer.

Specification

• Species: Monkey
• Source: HEK293
• Tag: His
• Protein Length: 33-473 aa
• Description: Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand.
• Form: Lyophilized from 0.22 μm filtered solution in PBS, 0.2 M Arginine, pH7.4 with trehalose as protectant.
• Molecular Mass: The protein has a calculated MW of 53.8 kDa. The protein migrates as 62-80 kDa when calibrated against Star Ribbon Pre-stained Protein Marker under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU/μg by the LAL method/rFC method.
• Purity: >95% as determined by SDS-PAGE.
• Storage: This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: NPR1 natriuretic peptide receptor 1 [ Macaca fascicularis (crab-eating macaque) ]
• Official Symbol: NPR1
• Synonyms: NPR1; natriuretic peptide receptor 1; atrial natriuretic peptide receptor 1; natriuretic peptide receptor A/guanylate cyclase A (atrionatriuretic peptide receptor A)
• Gene ID: 102143449
• mRNA Refseq: XM_005541753
• Protein Refseq: XP_005541810
• UniProt ID: G7NUH6