Recombinant Mouse Abcd1 Protein, His-tagged

• Cat.No.: Abcd1-12M
• Product Overview: Recombinant Mouse Abcd1 Protein (Pro447-Thr736) with N-His tag was expressed in E. coli.

Specification

• Species: Mouse
• Source: E.coli
• Tag: His
• Protein Length: Pro447-Thr736
• Description: The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ALD subfamily, which is involved in peroxisomal import of fatty acids and/or fatty acyl-CoAs in the organelle. All known peroxisomal ABC transporters are half transporters which require a partner half transporter molecule to form a functional homodimeric or heterodimeric transporter. This peroxisomal membrane protein is likely involved in the peroxisomal transport or catabolism of very long chain fatty acids. Defects in the human gene have been identified as the underlying cause of adrenoleukodystrophy, an X-chromosome recessively inherited demyelinating disorder of the nervous system.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 35.9 kDa
  Accurate Molecular Mass: 36 kDa
• Purity: > 90%
• Applications: Positive Control; Immunogen; SDS-PAGE; WB.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
• Storage Buffer: PBS, pH7.4, containing 0.01% SKL, 1 mM DTT, 5% Trehalose and Proclin300.
• Reconstitution: Reconstitute in sterile water to a concentration of 0.1-1.0 mg/mL. Do not vortex.

Gene Information

• Gene Name: Abcd1 ATP-binding cassette, sub-family D (ALD), member 1 [ Mus musculus (house mouse) ]
• Official Symbol: Abcd1
• Synonyms: ABCD1; ATP-binding cassette, sub-family D (ALD), member 1; ATP-binding cassette sub-family D member 1; adrenoleukodystrophy protein; ATP-binding cassette, sub-family D, member 1; X-linked adrenoleukodystrophy (ALD) gene homolog; Ald; ALDP; Aldgh
• Gene ID: 11666
• mRNA Refseq: NM_007435
• Protein Refseq: NP_031461
• UniProt ID: P48410