Recombinant Mouse Adipoq protein, His-tagged

• Cat.No.: Adipoq-204M
• Product Overview: Recombinant Mouse Adipoq protein(NP_033735.3)(Met1-Asn247), fused with His tag, was expressed in HEK293.

Specification

• Source: HEK293
• Species: Mouse
• Tag: His
• Form: Lyophilized from sterile PBS, pH 7.4Please contact us for any concerns or special requirements. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the hard copy of CoA.
• Molecular Mass: The secreted recombinant mouse ADIPOQ comprises 241 amino acids and has a calculated molecular mass of 26.4 kDa. As a result of glycosylation, the recombinant protein migrates as an approximately 30 kDa band in SDS-PAGE under reducing conditions.
• Proteinlength: Met1-Asn247
• Endotoxin: < 1.0 EU per μg of the protein as determined by the LAL method
• Purity: > 95 % as determined by SDS-PAGE
• Storage: Samples are stable for up to twelve months from date of receipt at -20°C to -80°C. Store it under sterile conditions at -20°C to -80°C. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 ug/ul. Centrifuge the vial at 4°C before opening to recover the entire contents.
• Protein length: Met1-Asn247
• Publication:
  Mucus mediated protection against acute colitis in adiponectin deficient mice. (2015)

Gene Information

• Gene Name: Adipoq adiponectin, C1Q and collagen domain containing [ Mus musculus ]
• Official Symbol: Adipoq
• Synonyms: ADIPOQ; adiponectin, C1Q and collagen domain containing; adiponectin; adipocyte-specific protein AdipoQ; adipocyte complement related protein; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30
• Gene ID: 11450
• mRNA Refseq: NM_009605
• Protein Refseq: NP_033735

Reviews

04/15/2019

the quality of the ADIPOQ protein used in experiments is of utmost importance and can significantly impact the accuracy and reliability of the results obtained.

05/12/2018

The packaging and shipping of the protein were both efficient and effective, ensuring that the product arrived in good condition and ready to use.

03/05/2018

The protein's stability and shelf-life have exceeded my expectations, allowing me to use it for multiple experiments without worrying about degradation or loss of potency.

09/04/2017

In this regard, using a protein of very high quality that meets your experimental needs is essential.

08/01/2016

It will ensure that your results are both valid and reproducible, providing you with valuable insights into the expression and function of ADIPOQ.

Q&As

Can ADIPOQ proteins be used in cancer treatment?

There is limited research on the use of ADIPOQ proteins in cancer treatment. However, some studies have suggested that ADIPOQ proteins may have a protective effect against certain types of cancers, including breast, colon, and prostate cancer.

Can ADIPOQ proteins be used in fertility treatments?

Various conditions and diseases can affect ADIPOQ protein levels, including type 2 diabetes, obesity, metabolic syndrome, polycystic ovary syndrome, and certain cancers.

Can ADIPOQ levels be modulated through lifestyle changes?

Yes, ADIPOQ levels can be modulated through lifestyle changes. Regular exercise and weight loss can increase ADIPOQ levels in the blood, while a diet high in saturated fats and sugar can decrease ADIPOQ levels.

Can ADIPOQ proteins have an impact on cardiovascular health?

Yes, ADIPOQ proteins have been shown to have a protective effect on cardiovascular health. High levels of ADIPOQ proteins are associated with lower risk of cardiovascular disease, while low levels of ADIPOQ proteins are associated with increased risk.

How can lifestyle changes affect ADIPOQ protein levels?

Lifestyle changes such as diet and exercise can significantly affect ADIPOQ protein levels. Eating a healthy diet and maintaining a healthy weight can increase circulating levels of ADIPOQ proteins, while sedentary lifestyle and obesity can decrease ADIPOQ protein levels.

How are ADIPOQ proteins related to obesity?

Low levels of ADIPOQ proteins in the circulation have been associated with obesity and an increased risk of metabolic disorders such as insulin resistance and type 2 diabetes. High levels of ADIPOQ proteins, on the other hand, have been associated with better insulin sensitivity and a lower risk of metabolic disorders.

Are there any medications that can affect ADIPOQ levels?

Some medications, such as thiazolidinediones (TZDs), commonly used to treat type 2 diabetes, can increase ADIPOQ levels and improve insulin sensitivity. However, other medications, such as glucocorticoids, used to treat inflammatory conditions, can reduce ADIPOQ levels and worsen insulin resistance.

How can ADIPOQ proteins be measured?

ADIPOQ protein levels can be measured in the circulation using a blood test or through adipose tissue biopsies. The blood test is a more commonly used diagnostic tool to evaluate ADIPOQ protein levels due to its non-invasive nature.

What are some conditions and diseases that may affect ADIPOQ protein levels?

Can ADIPOQ proteins be used as a biomarker for metabolic disorders?

Yes, measuring circulating levels of ADIPOQ proteins can be used as a biomarker for metabolic disorders such as insulin resistance and type 2 diabetes. Low levels of ADIPOQ proteins are associated with an increased risk of these disorders.

Are there any medications that target ADIPOQ proteins?

Currently, there are no medications that target ADIPOQ proteins directly. However, drugs that improve insulin sensitivity and metabolic function, such as thiazolidinediones (TZDs) and metformin, have been shown to increase circulating levels of ADIPOQ proteins.

What are some potential future applications of ADIPOQ proteins in medicine?

As research continues to explore the role of ADIPOQ proteins in various physiological processes, they may have potential future applications for the prevention and treatment of metabolic disorders, cardiovascular disease, infertility, and certain types of cancer. Additionally, ADIPOQ proteins may serve as a biomarker for disease and treatment response.