ADIPOQ

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ADIPOQ

Official Full Name adiponectin, C1Q and collagen domain containing
Background Important adipokine involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Stimulates AMPK phosphorylation and activation in the liver and the skeletal muscle, enhancing glucose utilization and fatty-acid combustion. Antagonizes TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. Inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. May play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex, LMW, MMW or HMW.
Synonyms ADIPOQ; adiponectin, C1Q and collagen domain containing; APN; Acdc; apM1; 30kDa; GBP28; adipo; Acrp30; adiponectin; adipocyte-specific protein AdipoQ; adipocyte complement related protein; 30 kDa adipocyte complement-related protein; adipocyte complement-related 30 kDa protein; adipocyte, C1Q and collagen domain containing; adipocyte, C1q and collagen domain-containing protein;
    • Species :
    • Cattle
    • Chicken
    • Dog
    • Human
    • Mouse
    • Pig
    • Porcine
    • Rat
    • Rhesus Macaque
    • Source :
    • CHO
    • E. coli
    • E.coli
    • HEK293
    • HEK293T
    • Human
    • Human Cell
    • Human cells
    • Human Serum
    • Insect Cell
    • Mammalian Cell
    • Mammalian cells
    • Porcine
    • Wheat Germ
    • Tag :
    • DDK
    • Fc
    • Flag
    • GST
    • His
    • S
    • T7
    • His-GST
    • human
    • IgG1
    • MYC/DDK
    • Myc
    • N/A
    Species Cat.# Product name Source (Host) Tag Protein Length Price
    Human ADIPOQ-610H Recombinant Human ADIPOQ protein, His-tagged E. coli His
    Human ACRP30-3197H Recombinant Human ACRP30 Insect Cell N/A
    Human ADIPOQ-02H Recombinant Human ADIPOQ Protein, His-tagged Insect cell His
    Human ADIPOQ-03H Recombinant Human ADIPOQ Protein E. coli
    Human ADIPOQ-1061H Recombinant Human Adiponectin Protein Human cells His
    Human ADIPOQ-1098H Recombinant Human ADIPOQ, Fc tagged Human Cell Fc
    Human ADIPOQ-133H Recombinant Human ADIPOQ protein, His-tagged Insect Cell His
    Human ADIPOQ-1376H Recombinant Human ADIPOQ Protein, MYC/DDK-tagged HEK293 Myc/DDK
    Human ADIPOQ-14H Recombinant Human ADIPOQ Protein, His/S-tagged E.coli His/S
    Human ADIPOQ-1526HCL Recombinant Human ADIPOQ cell lysate Human Cell N/A
    Human ADIPOQ-169H Recombinant Human Adiponectin, C1Q And Collagen Domain Containing Mammalian cells N/A
    Human ADIPOQ-1849H Recombinant Human Adiponectin, C1Q And Collagen Domain Containing E.coli N/A
    Human ADIPOQ-199H Recombinant Human ADIPOQ, His-tagged Insect Cell His
    Human ADIPOQ-19H Recombinant Human ACRP30 headless, FLAG-tagged HEK293 Flag
    Human ADIPOQ-209H Recombinant Human ADIPOQ, His-tagged E.coli His
    Human ADIPOQ-210H Recombinant Human ADIPOQ, His-tagged E.coli HIS
    Human ADIPOQ-211H Recombinant Human ADIPOQ HEK293 N/A
    Human ADIPOQ-215H Native Human Adiponectin Human Serum N/A
    Human ADIPOQ-251H Recombinant Human ADIPOQ protein, DDK-tagged Insect Cell DDK
    Human ADIPOQ-252H Recombinant Human ADIPOQ protein, DDK-tagged Insect Cell DDK
    Human ADIPOQ-253H Recombinant Human ADIPOQ protein, His-tagged HEK293 His
    Human ADIPOQ-254H Recombinant Human ADIPOQ protein, His-tagged Insect Cell His
    Human ADIPOQ-255H Recombinant Human ADIPOQ protein E.coli N/A
    Human ADIPOQ-256H Recombinant Human ADIPOQ protein, DDK-tagged CHO DDK
    Human ADIPOQ-3647H Recombinant Human ADIPOQ, His-tagged E.coli His
    Human ADIPOQ-391H Recombinant Human ADIPOQ Protein E.coli N/A
    Human ADIPOQ-392H Recombinant Human ADIPOQ Protein, GST-tagged Wheat Germ GST
    Human ADIPOQ-42H Recombinant Human ADIPOQ, Globular Domain, His-tagged E.coli His
    Human ADIPOQ-45H Recombinant Human ADIPOQ, Flag-tagged HEK293 N/A
    Human ADIPOQ-47H Recombinant Human ADIPOQ, Trimeric Form HEK293 N/A
    Human ADIPOQ-490H Recombinant Human Adiponectin, C1Q And Collagen Domain Containing HEK293 N/A
    Human ADIPOQ-4956H Recombinant Human Adiponectin, C1Q And Collagen Domain Containing Human N/A
    Human ADIPOQ-4957H Recombinant Human Adiponectin, C1Q And Collagen Domain Containing Human N/A
    Human ADIPOQ-693H Recombinant Human ADIPOQ, 145aa E.coli N/A
    Human ADIPOQ-7300H Recombinant Human ADIPOQ protein, His-tagged HEK293 His
    Human ADIPOQ-7301H Recombinant Human ADIPOQ protein, Fc-tagged HEK293 human/IgG1/Fc
    Human ADIPOQ-856H Recombinant Human ADIPOQ protein, Flag-tagged HEK293 Flag
    Mouse Adipoq-032M Recombinant Mouse Adipoq Protein, His-tagged E.coli His
    Mouse Adipoq-033M Recombinant Mouse Adipoq Protein, His-tagged Insect Cell His
    Mouse Adipoq-034M Recombinant Mouse Adipoq Protein E.coli
    Mouse Adipoq-035M Recombinant Mouse Adipoq Protein, MYC/DDK-tagged HEK293T MYC/DDK
    Mouse Adipoq-117M Recombinant Mouse Adipoq, Globular Domain, His-tagged E.coli His
    Mouse Adipoq-118M Recombinant Mouse Adipoq (Trimer), Flag-tagged HEK293 Flag
    Mouse ADIPOQ-1362M Recombinant Mouse ADIPOQ Protein, His-tagged Insect Cell His
    Mouse Adipoq-13M Recombinant Mouse Adiponectin Protein, His/S-tagged E.coli His/S
    Mouse Adipoq-204M Recombinant Mouse Adipoq, His tagged Human Cell His
    Mouse Adipoq-216M Recombinant Mouse Adipoq HEK293 N/A
    Mouse ADIPOQ-2209MCL Recombinant Mouse ADIPOQ cell lysate Human Cell N/A
    Mouse Adipoq-32M Recombinant Mouse Adipoq protein, Flag-tagged E.coli Flag
    Mouse Adipoq-33M Recombinant Mouse Adipoq protein, His-tagged E.coli His
    Mouse Adipoq-46M Recombinant Mouse Adipoq HEK293 N/A
    Mouse Adipoq-47M Recombinant Mouse Adiponectin, C1Q and Collagen Domain Containing, His-tagged E.coli His
    Mouse Adipoq-48M adiponectin, C1Q and collagen domain containing HEK293 N/A
    Mouse Adipoq-500M Recombinant Mouse Adipoq Protein E.coli N/A
    Mouse Adipoq-501M Recombinant Mouse Adipoq Protein, His-tagged Insect Cell His
    Mouse Adipoq-5373M Recombinant Mouse Adiponectin, C1Q And Collagen Domain Containing E.coli N/A
    Mouse Adipoq-5600M Recombinant Mouse Adiponectin, C1Q And Collagen Domain Containing, His-tagged Mammalian cells His
    Mouse Adipoq-7149M Recombinant Mouse Adipoq Protein E.coli
    Mouse Adipoq-7152M Recombinant Mouse Adipoq Protein HEK293
    Mouse Adipoq-7153M Recombinant Mouse Adipoq Protein, His-tagged E.coli His
    Mouse Adipoq-75M Recombinant Mouse Adiponectin, Globular Domain E.coli N/A
    Mouse Adipoq-79M Recombinant Mouse Adipoq, FLAG-tagged HEK293 Flag
    Rat Adipoq-194R Recombinant Rat Adipoq protein, His-tagged E.coli His
    Rat Adipoq-195R Recombinant Rat Adipoq, FLAG-tagged HEK293 Flag
    Rat Adipoq-502R Recombinant Rat Adipoq Protein E.coli N/A
    Rat Adipoq-5443R Recombinant Rat Adiponectin, C1Q And Collagen Domain Containing E.coli N/A
    Rhesus Macaque ADIPOQ-247R Recombinant Rhesus monkey ADIPOQ Protein, His-tagged Mammalian Cell His
    Dog ADIPOQ-188D Recombinant Dog ADIPOQ, FLAG-tagged HEK293 Flag
    Dog ADIPOQ-189D Recombinant Dog ADIPOQ, Globular Domain, FLAG-tagged HEK293 Flag
    Dog ADIPOQ-2646D Recombinant Dog ADIPOQ Protein, His-GST-tagged E.coli His-GST
    Chicken ADIPOQ-2647C Recombinant Chicken ADIPOQ protein, His & T7-tagged E.coli His/T7
    Chicken ADIPOQ-7114C Recombinant Chicken ADIPOQ Mammalian Cell His
    Porcine ADIPOQ-218P Recombinant Porcine ADIPOQ, Flag-tagged HEK293 Flag
    Cattle ADIPOQ-2645C Recombinant Cattle ADIPOQ protein, His-tagged E.coli His
    Pig ADIPOQ-2648P Recombinant Pig ADIPOQ protein, His & GST-tagged E.coli His/GST
    Porcine ADIPOQ-267P Recombinant Porcine Adiponectin, C1Q And Collagen Domain Containing, FLAG-tagged Porcine Flag

    ADIPOQ involved in several pathways and played different roles in them. We selected most pathways ADIPOQ participated on our site, such as PPAR signaling pathway, AMPK signaling pathway, Adipocytokine signaling pathway, which may be useful for your reference. Also, other proteins which involved in the same pathway with ADIPOQ were listed below. Creative BioMart supplied nearly all the proteins listed, you can search them on our site.

    Pathway Name Pathway Related Protein
    PPAR signaling pathway ACSL1A; GK2; SLC27A1B; PPARDB; RXRG; FABP4; CYP4A14; ACSBG2; APOC3; PLTP
    AMPK signaling pathway SCD5; PPP2R5C; AKT3; TBC1D1; RPS6KB2; CREB1; RPS6KB1; PRKAG1; PRKAG2; PPARG
    Adipocytokine signaling pathway PRKAA1; NFKBIAA; ACACB; PRKAG2; IKBKG; PRKAG1; SLC2A4; STK11; MAPK8B; ACSL5
    Type II diabetes mellitus INS2; MAPK10; PKLR; HKDC1; MTOR; IRS2; MAPK9; PIK3R3; INS1; PKM2
    Non-alcoholic fatty liver disease (NAFLD) IKBKB; RAC1; PIK3CG; SREBF1; TNFRSF1A; IL-8; SDHD; NDUFS5; GSK3B; SDHA

    ADIPOQ has several biochemical functions, for example, cytokine activity, hormone activity, identical protein binding. Some of the functions are cooperated with other proteins, some of the functions could acted by ADIPOQ itself. We selected most functions ADIPOQ had, and list some proteins which have the same functions with ADIPOQ. You can find most of the proteins on our site.

    Function Related Protein
    cytokine activity IL17D; CMTM6; TNFSF15; ILTIFB; CCL20A.3; GM13289; WNT7A; LEFTY1; WNT2; IL25
    hormone activity POMCA; MLN; INHBAB; C1QTNF9; ADIPOQ; GPHB5; NMB; PRL7D1; STC1L; PRL2A1
    identical protein binding MSTN; COL2A1; GLE1; NCAM1; GPSM2; CLPP; PARP1; GOT1; ACTN2; NEFL
    protein binding CETN2; R3HDM2; RAB1A; STRN; KRT33B; CCL20; RUSC1; RBMY1A1; TLK2; LANCL2
    protein homodimerization activity MYH9; FAP; UGT1A6A; ENPP1; CEBPA; CARD9; PML; ODZ4; ERBB4; CBLN1
    receptor binding EDN3; FGF1B; LRRC4B; ICOSLG; PAOX; MSTN; CSNK2B; CNPY4; SELPLG; TNFSF9
    sialic acid binding SELE; Siglece; L1CAM; SELP; AGRN; ST8SIA3; ADIPOQ; FCN1; ST8SIA2

    ADIPOQ has direct interactions with proteins and molecules. Those interactions were detected by several methods such as yeast two hybrid, co-IP, pull-down and so on. We selected proteins and molecules interacted with ADIPOQ here. Most of them are supplied by our site. Hope this information will be useful for your research of ADIPOQ.

    C1QTNF9B; C1QTNF9

    Cai, X; Gan, Y; et al. The adiponectin gene single-nucleotide polymorphism rs1501299 is associated with hepatocellular carcinoma risk. CLINICAL & TRANSLATIONAL ONCOLOGY 16:166-172(2014).
    Pang, YF; Dong, J; et al. Characterization, Neurosteroid Binding and Brain Distribution of Human Membrane Progesterone Receptors delta and epsilon (mPR delta and mPR epsilon) and mPR delta Involvement in Neurosteroid Inhibition of Apoptosis. ENDOCRINOLOGY 154:283-295(2013).

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