Recombinant Mouse Aplp2 Protein, His-tagged

• Cat.No.: Aplp2-11006M
• Product Overview: Mouse APLP2, His Tag is expressed from human 293 cells (HEK293). It contains AA Gly 32 - Ser 636 (Accession # Q06335-1). This protein carries a polyhistidine tag at the C-terminus. Predicted N-terminus: Gly 32

Specification

• Species: Mouse
• Source: HEK293
• Tag: His
• Protein Length: 32-636 aa
• Description: May play a role in the regulation of hemostasis. The soluble form may have inhibitory properties towards coagulation factors. May interact with cellular G-protein signaling pathways. May bind to the DNA 5'-GTCACATG-3'(CDEI box). Inhibits trypsin, chymotrypsin, plasmin, factor XIA and plasma and glandular kallikrein. Modulates the Cu/Zn nitric oxide-catalyzed autodegradation of GPC1 heparan sulfate side chains in fibroblasts.
• Form: Lyophilized from 0.22 μm filtered solution in PBS, pH7.4 with trehalose as protectant.
• Molecular Mass: The protein has a calculated MW of 71.5 kDa. The protein migrates as 80-90 kDa and 100 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
• Endotoxin: Less than 1.0 EU/μg by the LAL method/rFC method.
• Purity: >90% as determined by SDS-PAGE.
• Storage: This product is stable after storage at: -20 to -70 centigrade for 12 months in lyophilized state; -70 centigrade for 3 months under sterile conditions after reconstitution. For long term storage, the product should be stored at lyophilized state at -20 centigrade or lower. Please avoid repeated freeze-thaw cycles.
• Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.2 μg/μL. Centrifuge the vial at 4 centigrade before opening to recover the entire contents.

Gene Information

• Gene Name: Aplp2 amyloid beta (A4) precursor-like protein 2 [ Mus musculus ]
• Official Symbol: APLP2
• Synonyms: APLP2; amyloid beta (A4) precursor-like protein 2; amyloid-like protein 2; CDEBP; CDEI box-binding protein; APLP-2; AI790698
• Gene ID: 11804
• mRNA Refseq: NM_001102455
• Protein Refseq: NP_001095925
• UniProt ID: Q06335