Recombinant Mouse Arx Protein, MYC/DDK-tagged

• Cat.No.: Arx-652M
• Product Overview: Purified recombinant protein of full-length mouse aristaless related homeobox (Arx), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: This gene encodes a transcription factor that plays an important role in the development of forebrain. Male mice lacking this gene have smaller brains, olfactory bulbs and testes, and die within half a day after birth. Mice lacking this gene specifically in ganglionic eminence-derived neurons, including cortical interneurons, develop seizures. Mutations in this gene have been demonstrated to cause mouse phenotypes resembling human X-linked lissencephaly and cognitive disability with epilepsy. Alternative splicing results in multiple transcript variants.
• Molecular Mass: 58.9 kDa
• Purity: >80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Arx aristaless related homeobox [ Mus musculus (house mouse) ]
• Official Symbol: Arx
• Synonyms: Arx; aristaless related homeobox; Arx1; homeobox protein ARX
• Gene ID: 11878
• mRNA Refseq: NM_007492
• Protein Refseq: NP_031518
• UniProt ID: O35085